HitPredict

Interactor 1: UBP11 (P51784)
Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.4.19.12) (Deubiquitinating enzyme 11) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11)
Gene: USP11

Interactor 2: RING1 (Q06587)
E3 ubiquitin-protein ligase RING1 (EC 2.3.2.27) (Polycomb complex protein RING1) (RING finger protein 1) (RING-type E3 ubiquitin transferase RING1) (Really interesting new gene 1 protein)
Gene: RING1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.578

Property	Details
Experiments	20601937
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 963 Hs			1 406
+	Hs
		850161 UBP11_HUMAN (1-963): 0: 849: 100.00		RING2_HUMAN (8-406): 4.9e-100: 302: 54.25
+	Hs
		717585 UBP11_HUMAN (1-963): 0: 849: 100.00		BMI1_HUMAN (31-378): 4.06e-63: 207: 14.16
+	Hs
		718382 UBP11_HUMAN (1-963): 0: 849: 100.00		PCGF2_HUMAN (31-377): 1.44e-41: 151: 14.37
+	Hs
		749253 UBP11_HUMAN (1-963): 0: 849: 100.00		BRCA1_HUMAN (33-361): 4.24e-35: 139: 15.63
+	Hs
		584941 UBP4_HUMAN (73-933): 0: 656: 44.79		RO52_HUMAN (33-392): 4.67e-43: 158: 13.14
+	Hs
		988002 UBP7_HUMAN (607-959): 9.02e-54: 205: 15.17		RING1_HUMAN (1-406): 2.01e-114: 342: 100.00
+	Hs
		1257026 UBP33_HUMAN (223-945): 9.3e-109: 360: 18.55		PCGF6_HUMAN (31-157): 1.02e-40: 149: 23.08
+	Hs
		271189 UBP2_HUMAN (609-936): 9.85e-61: 220: 23.37		TRIM5_HUMAN (39-392): 3.48e-68: 225: 14.85
+	Hs
		718324 UBP22_HUMAN (597-930): 2.39e-62: 222: 17.88		BMI1_HUMAN (31-378): 4.06e-63: 207: 14.16
+	Hs
		749633 UBP37_HUMAN (294-954): 5.73e-83: 290: 16.41		BRCA1_HUMAN (33-361): 4.24e-35: 139: 15.63
+	Hs
		718079 UBP7_HUMAN (607-959): 9.02e-54: 205: 15.17		BMI1_HUMAN (31-378): 4.06e-63: 207: 14.16
+	Hs
		271032 UBP2_HUMAN (609-936): 9.85e-61: 220: 23.37		RO52_HUMAN (33-392): 4.67e-43: 158: 13.14
+	Hs
		271183 UBP2_HUMAN (609-936): 9.85e-61: 220: 23.37		PCGF6_HUMAN (31-157): 1.02e-40: 149: 23.08
+	Hs
		1223388 UBP7_HUMAN (607-959): 9.02e-54: 205: 15.17		TRI22_HUMAN (41-392): 2.66e-43: 159: 10.50
+	Hs
		271047 UBP2_HUMAN (609-936): 9.85e-61: 220: 23.37		BRCA1_HUMAN (33-361): 4.24e-35: 139: 15.63
+	Hs
		271195 UBP2_HUMAN (609-936): 9.85e-61: 220: 23.37		TRI39_HUMAN (39-392): 2e-35: 138: 13.84
+	Hs
		271184 UBP2_HUMAN (609-936): 9.85e-61: 220: 23.37		TRI34_HUMAN (39-392): 1.13e-34: 136: 10.43
+	Hs
		718415 UBP7_HUMAN (607-959): 9.02e-54: 205: 15.17		PCGF2_HUMAN (31-377): 1.44e-41: 151: 14.37
+	Hs
		1108527 UBP7_HUMAN (607-959): 9.02e-54: 205: 15.17		PCGF3_HUMAN (34-224): 6.2e-39: 141: 17.53
+	Hs
		749746 UBP7_HUMAN (607-959): 9.02e-54: 205: 15.17		BRCA1_HUMAN (33-361): 4.24e-35: 139: 15.63