HitPredict

Interactor 1: UBP11 (P51784)
Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.4.19.12) (Deubiquitinating enzyme 11) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11)
Gene: USP11

Interactor 2: TP4A2 (Q12974)
Protein tyrosine phosphatase type IVA 2 (EC 3.1.3.48) (HU-PP-1) (OV-1) (PTP(CAAXII)) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2)
Gene: PTP4A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	28330616, 28675297
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 963 Hs			1 167
+	Hs
		850137 UBP11_HUMAN (1-963): 0: 849: 100.00		TP4A1_HUMAN (1-167): 1.41e-66: 202: 87.65
+	Hs
		260534 UBP11_HUMAN (1-963): 0: 849: 100.00		TP4A3_HUMAN (1-166): 1.45e-64: 197: 77.52
+	Hs
		849972 UBP11_HUMAN (1-963): 0: 849: 100.00		PTEN_HUMAN (2-158): 1.56e-47: 160: 19.67
+	Hs
		260552 UBP4_HUMAN (73-933): 0: 656: 44.79		TP4A3_HUMAN (1-166): 1.45e-64: 197: 77.52
+	Hs
		890641 UBP4_HUMAN (73-933): 0: 656: 44.79		PTEN_HUMAN (2-158): 1.56e-47: 160: 19.67
+	Hs
		1167725 UBP33_HUMAN (223-945): 9.3e-109: 360: 18.55		TPTE2_HUMAN (6-159): 1.16e-47: 163: 16.00
+	Hs
		777024 UBP8_HUMAN (597-939): 3.73e-58: 219: 23.28		PTEN_HUMAN (2-158): 1.56e-47: 160: 19.67
+	Hs
		890786 UBP7_HUMAN (607-959): 9.02e-54: 205: 15.17		PTEN_HUMAN (2-158): 1.56e-47: 160: 19.67