HitPredict

Interactor 1: UBP11 (P51784)
Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.4.19.12) (Deubiquitinating enzyme 11) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11)
Gene: USP11

Interactor 2: UBP4 (Q13107)
Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Ubiquitous nuclear protein homolog)
Gene: USP4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.892

The method score is based on:

Property Details
Experiments 33567341, 19615732, 33961781, 22706160
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DUSP~DUSP, DUSP~Ubiquitin_3, Ubiquitin_3~Ubiquitin_3, UCH~UCH, UCH~USP7_C2
Common GO terms GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006508 - proteolysis
GO:0016579 - protein deubiquitination
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 963
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024