HitPredict

Interactor 1: UBP11 (P51784)
Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.4.19.12) (Deubiquitinating enzyme 11) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11)
Gene: USP11

Interactor 2: NEDD8 (Q15843)
NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8) (Ubiquitin-like protein Nedd8)
Gene: NEDD8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	DUSP~ubiquitin, UCH~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006508 - proteolysis
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 963 Hs			1 81
+	Hs
		849984 UBP11_HUMAN (1-963): 0: 849: 100.00		RL40_HUMAN (1-76): 3.79e-33: 112: 57.90
+	Hs
		924439 UBP20_HUMAN (223-939): 3.73e-108: 358: 17.79		RL40_HUMAN (1-76): 3.79e-33: 112: 57.90
+	Hs
		271114 UBP2_HUMAN (609-936): 9.85e-61: 220: 23.37		Q5U5U6_HUMAN (1-76): 2.4e-30: 107: 57.90
+	Hs
		924373 UBP7_HUMAN (607-959): 9.02e-54: 205: 15.17		RL40_HUMAN (1-76): 3.79e-33: 112: 57.90
+	Hs
		475123 UBP7_HUMAN (607-959): 9.02e-54: 205: 15.17		UBB_HUMAN (1-76): 2.4e-30: 107: 57.90