HitPredict

Interactor 1: UBP11 (P51784)
Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.4.19.12) (Deubiquitinating enzyme 11) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11)
Gene: USP11

Interactor 2: GGYF2 (Q6Y7W6)
GRB10-interacting GYF protein 2 (PERQ amino acid-rich with GYF domain-containing protein 2) (Trinucleotide repeat-containing gene 15 protein)
Gene: GIGYF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	36490346, 19615732
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 963 Hs			1 1299
+	Hs
		725119 UBP11_HUMAN (1-963): 0: 849: 100.00		MYH10_HUMAN (351-1292): 8.75e-26: 118: 10.28
+	Hs
		724724 UBP11_HUMAN (1-963): 0: 849: 100.00		MYH9_HUMAN (349-1161): 1.1e-19: 98.3: 10.26
+	Hs
		850101 UBP11_HUMAN (1-963): 0: 849: 100.00		MYH14_HUMAN (719-1022): 6.74e-10: 66.2: 19.94
+	Hs
		1024337 UBP4_HUMAN (73-933): 0: 656: 44.79		PLEC_HUMAN (324-1292): 6.24e-14: 79.4: 8.88
+	Hs
		1024411 UBP4_HUMAN (73-933): 0: 656: 44.79		SLK_HUMAN (753-1031): 1.3e-09: 65: 17.39
+	Hs
		1167944 UBP7_HUMAN (607-959): 9.02e-54: 205: 15.17		GGYF2_HUMAN (1-1299): 4.85e-105: 364: 100.00
+	Hs
		725271 UBP20_HUMAN (223-939): 3.73e-108: 358: 17.79		MYH10_HUMAN (351-1292): 8.75e-26: 118: 10.28
+	Hs
		725080 UBP20_HUMAN (223-939): 3.73e-108: 358: 17.79		MYH9_HUMAN (349-1161): 1.1e-19: 98.3: 10.26
+	Hs
		264435 UBP21_HUMAN (778-935): 1.96e-48: 183: 38.61		GGYF1_HUMAN (1-619): 2.01e-71: 261: 46.64
+	Hs
		1068706 UBP20_HUMAN (223-939): 3.73e-108: 358: 17.79		PLEC_HUMAN (324-1292): 6.24e-14: 79.4: 8.88
+	Hs
		725186 UBP45_HUMAN (169-929): 6.98e-93: 314: 16.85		MYH10_HUMAN (351-1292): 8.75e-26: 118: 10.28
+	Hs
		724889 UBP45_HUMAN (169-929): 6.98e-93: 314: 16.85		MYH9_HUMAN (349-1161): 1.1e-19: 98.3: 10.26
+	Hs
		876533 UBP21_HUMAN (778-935): 1.96e-48: 183: 38.61		AFAD_HUMAN (299-880): 8.47e-55: 212: 16.30
+	Hs
		271039 UBP2_HUMAN (609-936): 9.85e-61: 220: 23.37		MYH9_HUMAN (349-1161): 1.1e-19: 98.3: 10.26
+	Hs
		1067455 UBP7_HUMAN (607-959): 9.02e-54: 205: 15.17		EEA1_HUMAN (664-1295): 2.56e-22: 106: 9.35
+	Hs
		1273954 UBP7_HUMAN (607-959): 9.02e-54: 205: 15.17		MYH13_HUMAN (352-1268): 8.47e-20: 98.7: 10.42
+	Hs
		724949 UBP7_HUMAN (607-959): 9.02e-54: 205: 15.17		MYH9_HUMAN (349-1161): 1.1e-19: 98.3: 10.26
+	Hs
		1068624 UBP7_HUMAN (607-959): 9.02e-54: 205: 15.17		PLEC_HUMAN (324-1292): 6.24e-14: 79.4: 8.88
+	Mm
		1186813 UBP15_MOUSE (493-644): 8.98e-18: 90.8: 10.06		MRCKB_MOUSE (609-1109): 2.19e-21: 103: 12.45
+	Mm
		1143171 UBP15_MOUSE (493-644): 8.98e-18: 90.8: 10.06		MYH10_MOUSE (739-1030): 1.45e-09: 65: 16.72