HitPredict

Interactor 1: UBP11 (P51784)
Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.4.19.12) (Deubiquitinating enzyme 11) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11)
Gene: USP11

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	31504778
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 963 Hs			1 488
+	Hs
		850032 UBP11_HUMAN (1-963): 0: 849: 100.00		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1024388 UBP4_HUMAN (73-933): 0: 656: 44.79		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		1174179 UBP43_HUMAN (285-938): 2.36e-115: 382: 23.78		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		1038483 UBP43_HUMAN (285-938): 2.36e-115: 382: 23.78		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1198261 UBP37_HUMAN (294-954): 5.73e-83: 290: 16.41		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		1038495 UBP37_HUMAN (294-954): 5.73e-83: 290: 16.41		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1038600 UBP7_HUMAN (607-959): 9.02e-54: 205: 15.17		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		301427 UBP19_HUMAN (496-656): 3.05e-21: 102: 7.96		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		301388 UBP19_HUMAN (496-656): 3.05e-21: 102: 7.96		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Mm
		1193546 UBP8_MOUSE (597-933): 2.86e-58: 219: 23.68		Q8CGC3_MOUSE (11-367): 2.52e-102: 332: 23.93
+	Hs
		1273941 UBP7_HUMAN (607-959): 9.02e-54: 205: 15.17		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04
+	Hs
		1329994 UBP15_HUMAN (485-644): 1.32e-17: 90.4: 10.18		Q9H368_HUMAN (212-429): 3.07e-78: 245: 51.80