HitPredict

Interactor 1: UBP11 (P51784)
Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.4.19.12) (Deubiquitinating enzyme 11) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11)
Gene: USP11

Interactor 2: UBP7 (Q93009)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: USP7

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 30367141, 30804394, 36490346, 19615732, 20601937, 26496610, 33567341, 22411829
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains UCH~UCH, UCH~USP7_C2, USP7_C2~USP7_C2, USP7_C2~USP7_ICP0_bdg
Common GO terms GO:0004197 - cysteine-type endopeptidase activity
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005694 - chromosome
and 3 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 963
Hs

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Last updated: 15 Jul 2024