HitPredict

Interactor 1: PLXA3 (P51805)
Plexin-A3 (Plexin-4) (Semaphorin receptor SEX)
Gene: PLXNA3

Interactor 2: CLC2B (Q92478)
C-type lectin domain family 2 member B (Activation-induced C-type lectin) (C-type lectin superfamily member 2) (IFN-alpha-2b-inducing-related protein 1)
Gene: CLEC2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1871 Hs			1 149
+	Hs
		644548 PLXA3_HUMAN (1-1871): 0: 2527: 100.00		NKG2A_HUMAN (8-148): 1.03e-39: 135: 26.75
+	Hs
		850476 PLXA3_HUMAN (1-1871): 0: 2527: 100.00		CL12B_HUMAN (19-146): 3.08e-35: 124: 31.66
+	Hs
		1329769 PLXA1_HUMAN (11-1871): 0: 2480: 66.95		CLC4M_HUMAN (32-148): 2.16e-43: 148: 34.11
+	Hs
		644655 PLXA1_HUMAN (11-1871): 0: 2480: 66.95		NKG2A_HUMAN (8-148): 1.03e-39: 135: 26.75
+	Hs
		1100817 PLXA1_HUMAN (11-1871): 0: 2480: 66.95		CL12B_HUMAN (19-146): 3.08e-35: 124: 31.66
+	Hs
		1028535 PLXA1_HUMAN (11-1871): 0: 2480: 66.95		KLRD1_HUMAN (25-148): 9.94e-33: 115: 26.72
+	Hs
		253452 PLXA2_HUMAN (16-1871): 0: 2424: 59.96		NKG2A_HUMAN (8-148): 1.03e-39: 135: 26.75
+	Hs
		253468 PLXA2_HUMAN (16-1871): 0: 2424: 59.96		CL12B_HUMAN (19-146): 3.08e-35: 124: 31.66
+	Hs
		253509 PLXA2_HUMAN (16-1871): 0: 2424: 59.96		CLC4A_HUMAN (16-147): 7.74e-35: 122: 23.13
+	Hs
		165230 PLXB2_HUMAN (26-1869): 0: 1946: 31.05		CLC2B_HUMAN (1-149): 1.2e-43: 142: 100.00
+	Hs
		165162 PLXB2_HUMAN (26-1869): 0: 1946: 31.05		NKG2A_HUMAN (8-148): 1.03e-39: 135: 26.75
+	Hs
		165206 PLXB2_HUMAN (26-1869): 0: 1946: 31.05		CL12B_HUMAN (19-146): 3.08e-35: 124: 31.66
+	Hs
		1027979 SEM3B_HUMAN (5-557): 5.05e-132: 433: 17.31		PGCB_HUMAN (8-146): 1.28e-43: 154: 18.54
+	Hs
		644615 SEM4D_HUMAN (2-541): 3.24e-120: 404: 16.19		NKG2A_HUMAN (8-148): 1.03e-39: 135: 26.75
+	Hs
		1100777 SEM4D_HUMAN (2-541): 3.24e-120: 404: 16.19		CL12B_HUMAN (19-146): 3.08e-35: 124: 31.66
+	Hs
		981902 RON_HUMAN (792-1219): 6.34e-101: 359: 24.95		CLC2B_HUMAN (1-149): 1.2e-43: 142: 100.00