HitPredict

Interactor 1: DYLT3 (P51808)
Dynein light chain Tctex-type 3 (Protein 91/23) (T-complex-associated testis-expressed 1-like)
Gene: DYNLT3

Interactor 2: DYT2B (Q8WW35)
Dynein light chain Tctex-type protein 2B (Tctex1 domain-containing protein 2)
Gene: DYNLT2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	27173435
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Tctex-1~Tctex-1
Common GO terms	GO:0005737 - cytoplasm GO:0005868 - cytoplasmic dynein complex GO:0007018 - microtubule-based movement GO:0045505 - dynein intermediate chain binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 116 Hs			1 142
+	Hs
		928647 DYLT1_HUMAN (1-114): 9.84e-46: 145: 53.51		DYT2B_HUMAN (1-142): 3.88e-67: 201: 100.00
+	Dm
		1276661 DYLT_DROME (5-114): 3.35e-42: 136: 46.36		Q9VH45_DROME (12-142): 1.79e-50: 160: 32.84
+	Hs
		928610 DYLT1_HUMAN (1-114): 9.84e-46: 145: 53.51		DYLT4_HUMAN (7-140): 3.12e-44: 145: 33.58
+	Hs
		850524 DYLT3_HUMAN (1-116): 4.5e-47: 148: 100.00		DYLT3_HUMAN (32-139): 2.77e-43: 140: 22.22
+	Cr
		249526 O64980_CHLRE (1-114): 7.15e-46: 145: 45.61		O64980_CHLRE (31-139): 6.68e-43: 139: 26.55
+	Hs
		850527 DYLT3_HUMAN (1-116): 4.5e-47: 148: 100.00		DYLT1_HUMAN (35-139): 5.61e-41: 134: 29.36
+	Hs
		928580 DYLT1_HUMAN (1-114): 9.84e-46: 145: 53.51		DYLT1_HUMAN (35-139): 5.61e-41: 134: 29.36
+	Hs
		1127236 DYT2B_HUMAN (2-111): 1.38e-36: 123: 21.24		DYLT4_HUMAN (7-140): 3.12e-44: 145: 33.58
+	Dm
		1276651 DYLT_DROME (5-114): 3.35e-42: 136: 46.36		DYLT_DROME (34-139): 6.46e-40: 131: 24.55
+	Dm
		1178518 DYLT_DROME (5-114): 3.35e-42: 136: 46.36		Q7K035_DROME (28-141): 2.04e-37: 127: 26.09