HitPredict

Interactor 1: KS6A3 (P51812)
Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)
Gene: RPS6KA3

Interactor 2: BCAR1 (P56945)
Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas)
Gene: BCAR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	33001583, 36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019901 - protein kinase binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 740 Hs			1 870
+	Hs
		882312 KS6A1_HUMAN (1-740): 0: 783: 77.90		BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00
+	Hs
		272856 KS6A4_HUMAN (59-739): 0: 646: 40.81		BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00
+	Hs
		1057021 KS6A6_HUMAN (1-740): 0: 771: 76.54		MDC1_HUMAN (48-774): 9.36e-10: 64.9: 9.16
+	Hs
		272890 KS6A4_HUMAN (59-739): 0: 646: 40.81		SH3K1_HUMAN (7-294): 1.08e-16: 86.7: 16.44
+	Hs
		1071717 KS6A2_HUMAN (7-327): 3.91e-100: 326: 24.02		MACF1_HUMAN (505-867): 1.44e-74: 269: 13.79
+	Hs
		681809 AKT1_HUMAN (327-739): 2.87e-125: 383: 21.02		ACK1_HUMAN (9-499): 2.55e-30: 131: 15.35