HitPredict

Interactor 1: KS6A3 (P51812)
Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)
Gene: RPS6KA3

Interactor 2: EIF3C (Q99613)
Eukaryotic translation initiation factor 3 subunit C (eIF3c) (Eukaryotic translation initiation factor 3 subunit 8) (eIF3 p110)
Gene: EIF3C

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	21900206
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 740 Hs			1 913
+	Hs
		616727 KS6B1_HUMAN (397-727): 8.14e-116: 361: 25.50		EIF3C_HUMAN (1-913): 0: 1213: 100.00
+	Rn
		78195 AKT3_RAT (390-739): 1.71e-123: 379: 22.10		EIF3C_RAT (1-913): 0: 1174: 95.51
+	Hs
		1071687 KS6A2_HUMAN (7-327): 3.91e-100: 326: 24.02		EIF3C_HUMAN (1-913): 0: 1213: 100.00
+	Hs
		78307 KS6A2_HUMAN (7-327): 3.91e-100: 326: 24.02		EIFCL_HUMAN (1-913): 0: 1209: 99.13
+	Dm
		55554 JIL1_DROME (420-729): 6.72e-96: 324: 25.00		EIF3C_DROME (1-898): 0: 980: 50.33
+	Dm
		55567 Q9VR61_DROME (2-328): 3.5e-90: 304: 23.68		EIF3C_DROME (1-898): 0: 980: 50.33
+	At
		221478 KPK1_ARATH (420-715): 5.66e-102: 322: 28.48		EIF3C_ARATH (214-894): 0: 751: 36.69