HitPredict

Interactor 1: BMX (P51813)
Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38)
Gene: BMX

Interactor 2: RAP1A (P62834)
Ras-related protein Rap-1A (EC 3.6.5.2) (C21KG) (G-22K) (GTP-binding protein smg p21A) (Ras-related protein Krev-1)
Gene: RAP1A

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	1.00	0.747

Property	Details
Experiments	15207703
Identification Methods	pull down, antibody array, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 675 Hs			1 184
+	Hs
		350101 BTK_HUMAN (5-673): 0: 661: 47.41		RASK_HUMAN (1-184): 8.24e-56: 176: 54.45
+	Hs
		349264 BTK_HUMAN (5-673): 0: 661: 47.41		RASH_HUMAN (1-180): 7.38e-55: 173: 55.00
+	Hs
		412123 FYN_HUMAN (131-668): 7.58e-177: 516: 29.38		RAC1_HUMAN (1-184): 1.19e-73: 221: 29.08
+	Hs
		522888 SRC_HUMAN (145-668): 9.1e-172: 503: 30.74		RAC1_HUMAN (1-184): 1.19e-73: 221: 29.08
+	Hs
		433314 YES_HUMAN (132-668): 8.1e-171: 501: 28.42		RAC1_HUMAN (1-184): 1.19e-73: 221: 29.08
+	Hs
		522882 SRC_HUMAN (145-668): 9.1e-172: 503: 30.74		RB11A_HUMAN (4-178): 2.1e-71: 216: 28.41
+	Hs
		433312 YES_HUMAN (132-668): 8.1e-171: 501: 28.42		RB11A_HUMAN (4-178): 2.1e-71: 216: 28.41
+	Hs
		523004 SRC_HUMAN (145-668): 9.1e-172: 503: 30.74		RB11B_HUMAN (4-173): 1.69e-70: 214: 30.41
+	Hs
		789109 FRK_HUMAN (189-668): 6.8e-160: 471: 33.94		RAC1_HUMAN (1-184): 1.19e-73: 221: 29.08
+	Hs
		433685 LYN_HUMAN (141-669): 2.18e-159: 470: 29.70		RAC1_HUMAN (1-184): 1.19e-73: 221: 29.08
+	Hs
		349066 FYN_HUMAN (131-668): 7.58e-177: 516: 29.38		RASH_HUMAN (1-180): 7.38e-55: 173: 55.00
+	Hs
		433683 LYN_HUMAN (141-669): 2.18e-159: 470: 29.70		RAP1A_HUMAN (1-184): 5.85e-73: 219: 100.00
+	Hs
		349836 SRC_HUMAN (145-668): 9.1e-172: 503: 30.74		RASK_HUMAN (1-184): 8.24e-56: 176: 54.45
+	Hs
		349806 YES_HUMAN (132-668): 8.1e-171: 501: 28.42		RASK_HUMAN (1-184): 8.24e-56: 176: 54.45
+	Hs
		349095 SRC_HUMAN (145-668): 9.1e-172: 503: 30.74		RASH_HUMAN (1-180): 7.38e-55: 173: 55.00
+	Hs
		349069 YES_HUMAN (132-668): 8.1e-171: 501: 28.42		RASH_HUMAN (1-180): 7.38e-55: 173: 55.00
+	Rn
		589762 SRC_RAT (145-668): 7.35e-170: 498: 30.74		RASH_RAT (1-180): 7.38e-55: 173: 55.00
+	Hs
		349807 LYN_HUMAN (141-669): 2.18e-159: 470: 29.70		RASK_HUMAN (1-184): 8.24e-56: 176: 54.45
+	Hs
		349070 LYN_HUMAN (141-669): 2.18e-159: 470: 29.70		RASH_HUMAN (1-180): 7.38e-55: 173: 55.00
+	Hs
		349172 ABL2_HUMAN (200-673): 1.14e-149: 465: 33.12		RASH_HUMAN (1-180): 7.38e-55: 173: 55.00