HitPredict

Interactor 1: BMX (P51813)
Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38)
Gene: BMX

Interactor 2: C2D1B (Q5T0F9)
Coiled-coil and C2 domain-containing protein 1B (Five prime repressor element under dual repression-binding protein 2) (FRE under dual repression-binding protein 2) (Freud-2)
Gene: CC2D1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	C2~SH2
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 675 Hs			1 858
+	Hs
		522749 SRC_HUMAN (145-668): 9.1e-172: 503: 30.74		MUC1_HUMAN (179-672): 5.79e-19: 94.8: 8.89
+	Hs
		411823 LCK_HUMAN (132-669): 7.18e-166: 487: 29.95		ASPP1_HUMAN (111-544): 5.73e-21: 100: 12.85
+	Hs
		411582 LCK_HUMAN (132-669): 7.18e-166: 487: 29.95		MUC1_HUMAN (179-672): 5.79e-19: 94.8: 8.89
+	Hs
		433948 LYN_HUMAN (141-669): 2.18e-159: 470: 29.70		ASPP1_HUMAN (111-544): 5.73e-21: 100: 12.85
+	Mm
		101424 LYN_MOUSE (141-669): 1.9e-161: 475: 30.64		F8VPR5_MOUSE (41-504): 9.54e-19: 94.1: 9.57
+	Hs
		337335 ABL1_HUMAN (178-673): 2.31e-153: 474: 31.94		MUC1_HUMAN (179-672): 5.79e-19: 94.8: 8.89
+	Hs
		433560 LYN_HUMAN (141-669): 2.18e-159: 470: 29.70		MUC1_HUMAN (179-672): 5.79e-19: 94.8: 8.89
+	Hs
		203198 LCK_HUMAN (132-669): 7.18e-166: 487: 29.95		SYNJ1_HUMAN (345-732): 3.1e-09: 63.3: 10.61
+	Mm
		101430 CSK_MOUSE (200-675): 1.1e-154: 456: 32.43		F8VPR5_MOUSE (41-504): 9.54e-19: 94.1: 9.57
+	Hs
		152571 ABL1_HUMAN (178-673): 2.31e-153: 474: 31.94		KMT2D_HUMAN (222-526): 5.34e-09: 62.7: 13.31
+	Hs
		297808 LYN_HUMAN (141-669): 2.18e-159: 470: 29.70		K0754_HUMAN (2-234): 6.19e-09: 62.1: 12.88
+	Hs
		433853 LYN_HUMAN (141-669): 2.18e-159: 470: 29.70		MICA3_HUMAN (192-703): 7.59e-09: 61.7: 12.38