HitPredict

Interactor 1: GUC2F (P51841)
Retinal guanylyl cyclase 2 (RETGC-2) (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (Guanylate cyclase F) (GC-F) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2)
Gene: GUCY2F

Interactor 2: GUC2D (Q02846)
Retinal guanylyl cyclase 1 (RETGC-1) (EC 4.6.1.2) (CG-E) (Guanylate cyclase 2D, retinal) (Rod outer segment membrane guanylate cyclase) (ROS-GC)
Gene: GUCY2D

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ANF_receptor~ANF_receptor, Guanylate_cyc~Guanylate_cyc, Guanylate_cyc~HNOBA, HNOBA~HNOBA, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr
Common GO terms GO:0001653 - peptide receptor activity
GO:0004016 - adenylate cyclase activity
GO:0004383 - guanylate cyclase activity
GO:0004672 - protein kinase activity
GO:0005524 - ATP binding
and 11 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1108
Hs

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Last updated: 15 Jul 2024