HitPredict

Interactor 1: HDGF (P51858)
Hepatoma-derived growth factor (HDGF) (High mobility group protein 1-like 2) (HMG-1L2)
Gene: HDGF

Interactor 2: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	21907836
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~PWWP
Common GO terms	GO:0005615 - extracellular space GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 240 Hs			1 126
+	Hs
		850890 HDGF_HUMAN (1-240): 4.63e-53: 173: 100.00		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		241483 HDGF_HUMAN (1-240): 4.63e-53: 173: 100.00		H2B1K_HUMAN (1-126): 1.56e-53: 165: 98.41
+	Hs
		850880 HDGF_HUMAN (1-240): 4.63e-53: 173: 100.00		H2B1D_HUMAN (1-126): 3.5e-53: 164: 98.41
+	Hs
		855491 MSH6_HUMAN (5-232): 3.82e-46: 165: 18.55		H2B2F_HUMAN (1-126): 2.34e-54: 168: 97.62
+	Hs
		855449 MSH6_HUMAN (5-232): 3.82e-46: 165: 18.55		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		855488 MSH6_HUMAN (5-232): 3.82e-46: 165: 18.55		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		1087155 GLYR1_HUMAN (6-228): 2.27e-46: 163: 25.94		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		855445 MSH6_HUMAN (5-232): 3.82e-46: 165: 18.55		H2B1D_HUMAN (1-126): 3.5e-53: 164: 98.41
+	Hs
		918404 GLYR1_HUMAN (6-228): 2.27e-46: 163: 25.94		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		1087480 ZMYD8_HUMAN (3-233): 1.74e-41: 152: 20.59		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		918769 ZMYD8_HUMAN (3-233): 1.74e-41: 152: 20.59		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		707787 ZMYD8_HUMAN (3-233): 1.74e-41: 152: 20.59		H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41
+	Hs
		1087385 NSD3_HUMAN (8-222): 4.17e-37: 140: 16.74		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		265986 PSIP1_HUMAN (7-239): 7.38e-38: 140: 37.60		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		266023 PSIP1_HUMAN (7-239): 7.38e-38: 140: 37.60		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		266045 PSIP1_HUMAN (7-239): 7.38e-38: 140: 37.60		H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41
+	Hs
		918663 NSD3_HUMAN (8-222): 4.17e-37: 140: 16.74		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		707738 NSD3_HUMAN (8-222): 4.17e-37: 140: 16.74		H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41
+	Hs
		331768 NSD2_HUMAN (9-226): 4.97e-34: 131: 19.18		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		331825 NSD2_HUMAN (9-226): 4.97e-34: 131: 19.18		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00