HitPredict

Interactor 1: HDGF (P51858)
Hepatoma-derived growth factor (HDGF) (High mobility group protein 1-like 2) (HMG-1L2)
Gene: HDGF

Interactor 2: HDGR2 (Q7Z4V5)
Hepatoma-derived growth factor-related protein 2 (HDGF-related protein 2) (HRP-2) (Hepatoma-derived growth factor 2) (HDGF-2)
Gene: HDGFL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	33961781, 35235311
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PWWP~PWWP
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0006338 - chromatin remodeling
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 240 Hs			1 671
+	Mm
		851010 HDGF_MOUSE (1-240): 2.86e-49: 163: 85.83		HDGR2_MOUSE (1-671): 8.94e-74: 252: 70.34
+	Hs
		266032 PSIP1_HUMAN (7-239): 7.38e-38: 140: 37.60		HDGR2_HUMAN (1-671): 9.52e-82: 274: 100.00
+	Hs
		331751 HDGF_HUMAN (1-240): 4.63e-53: 173: 100.00		NSD2_HUMAN (3-440): 5.42e-66: 238: 11.70
+	Hs
		1190745 HDGR3_HUMAN (5-209): 6.28e-36: 127: 47.83		HDGR2_HUMAN (1-671): 9.52e-82: 274: 100.00
+	Hs
		1115577 GLYR1_HUMAN (6-228): 2.27e-46: 163: 25.94		NSD3_HUMAN (4-413): 2.6e-62: 227: 11.66
+	Hs
		265971 HDGF_HUMAN (1-240): 4.63e-53: 173: 100.00		PSIP1_HUMAN (1-553): 1.35e-54: 197: 23.49
+	Hs
		331678 NSD2_HUMAN (9-226): 4.97e-34: 131: 19.18		NSD2_HUMAN (3-440): 5.42e-66: 238: 11.70
+	Hs
		1317717 NSD3_HUMAN (8-222): 4.17e-37: 140: 16.74		NSD3_HUMAN (4-413): 2.6e-62: 227: 11.66
+	Hs
		517806 GLYR1_HUMAN (6-228): 2.27e-46: 163: 25.94		NFH_HUMAN (4-506): 1.46e-35: 146: 10.52