HitPredict

Interactor 1: NEK2 (P51955)
Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1)
Gene: NEK2

Interactor 2: NEK2 (P51955)
Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1)
Gene: NEK2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.863

The method score is based on:

Property Details
Experiments 23288039, 10347187, 18086858
Identification Methods affinity chromatography technology, two hybrid, pull down, in-gel kinase assay, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, phosphorylation reaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000278 - mitotic cell cycle
GO:0000776 - kinetochore
GO:0000794 - condensed nuclear chromosome
GO:0000922 - spindle pole
GO:0001824 - blastocyst development
and 30 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 445
Hs

1 445
+ Gm
+ At
+ At
+ At
+ At
+ At
+ At
+ Rn
+ Zm
+ At
+ Hs
+ At
+ At
+ At
+ At
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024