HitPredict

Interactor 1: NEK4 (P51957)
Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2)
Gene: NEK4

Interactor 2: CC136 (Q96JN2)
Coiled-coil domain-containing protein 136 (Nasopharyngeal carcinoma-associated gene 6 protein)
Gene: CCDC136

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	25798074
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 841 Hs			1 1154
+	Hs
		724727 NEK4_HUMAN (1-841): 0: 617: 100.00		MYH9_HUMAN (362-1142): 3.6e-30: 132: 11.84
+	Hs
		851713 NEK4_HUMAN (1-841): 0: 617: 100.00		DAPLE_HUMAN (28-987): 1.43e-26: 120: 13.31
+	Hs
		522572 SNRK_HUMAN (6-734): 3.73e-131: 411: 15.35		MYH1_HUMAN (184-1132): 5.05e-39: 161: 9.95
+	Hs
		1344754 SNRK_HUMAN (6-734): 3.73e-131: 411: 15.35		MYH2_HUMAN (2-906): 7.49e-39: 160: 11.44
+	Hs
		724967 MARK4_HUMAN (3-718): 6.32e-132: 413: 19.05		MYH9_HUMAN (362-1142): 3.6e-30: 132: 11.84
+	Hs
		725010 SIK2_HUMAN (1-725): 1.09e-128: 409: 16.65		MYH9_HUMAN (362-1142): 3.6e-30: 132: 11.84
+	Mm
		93559 TAOK2_MOUSE (2-835): 7.21e-133: 428: 16.43		DESP_MOUSE (35-809): 1.51e-22: 107: 12.82
+	Hs
		725223 MARK4_HUMAN (3-718): 6.32e-132: 413: 19.05		MYH10_HUMAN (5-613): 3.84e-20: 99.5: 13.83
+	Hs
		1268126 MRCKB_HUMAN (3-840): 5.02e-132: 433: 16.63		MY18A_HUMAN (26-640): 6.72e-14: 79.1: 17.39
+	Hs
		1137917 MRCKB_HUMAN (3-840): 5.02e-132: 433: 16.63		MRCKA_HUMAN (7-389): 1.31e-13: 78.2: 14.82
+	Hs
		725242 SIK2_HUMAN (1-725): 1.09e-128: 409: 16.65		MYH10_HUMAN (5-613): 3.84e-20: 99.5: 13.83
+	Rn
		1186812 MRCKB_RAT (3-840): 1.99e-134: 440: 16.97		MRCKB_RAT (711-1101): 1.77e-10: 67.8: 12.87
+	Hs
		1137871 MRCKA_HUMAN (3-780): 2.99e-129: 426: 19.17		MRCKA_HUMAN (7-389): 1.31e-13: 78.2: 14.82
+	Rn
		222476 MRCKB_RAT (3-840): 1.99e-134: 440: 16.97		MRCKA_RAT (689-1077): 5.52e-09: 62.8: 11.84
+	Hs
		1189798 SIK2_HUMAN (1-725): 1.09e-128: 409: 16.65		MYH14_HUMAN (295-1097): 9.71e-17: 88.2: 13.64
+	Rn
		222472 MRCKA_RAT (3-780): 5.46e-132: 434: 19.05		MRCKA_RAT (689-1077): 5.52e-09: 62.8: 11.84
+	Hs
		1268074 MARK4_HUMAN (3-718): 6.32e-132: 413: 19.05		MY18A_HUMAN (26-640): 6.72e-14: 79.1: 17.39
+	Hs
		728513 SIK2_HUMAN (1-725): 1.09e-128: 409: 16.65		MYH11_HUMAN (3-421): 1.51e-10: 67.9: 13.15