HitPredict

Interactor 1: NEK4 (P51957)
Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2)
Gene: NEK4

Interactor 2: IF2B1 (Q9NZI8)
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2 mRNA-binding protein 1) (IMP-1) (IMP1) (Coding region determinant-binding protein) (CRD-BP) (IGF-II mRNA-binding protein 1) (VICKZ family member 1) (Zipcode-binding protein 1) (ZBP-1)
Gene: IGF2BP1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	25798074
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 841 Hs			1 577
+	Hs
		128078 NEK4_HUMAN (1-841): 0: 617: 100.00		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Hs
		1349153 KS6B2_HUMAN (6-405): 5.48e-130: 399: 21.79		IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00
+	Hs
		851501 NEK4_HUMAN (1-841): 0: 617: 100.00		PCBP2_HUMAN (407-575): 6.35e-44: 162: 27.43
+	Hs
		851621 NEK4_HUMAN (1-841): 0: 617: 100.00		FUBP2_HUMAN (118-416): 2.4e-14: 78.1: 15.89
+	Hs
		851500 NEK4_HUMAN (1-841): 0: 617: 100.00		PCBP1_HUMAN (476-574): 1.53e-12: 71: 17.17
+	Hs
		682197 AKT2_HUMAN (1-333): 1.36e-134: 411: 22.12		FUBP2_HUMAN (118-416): 2.4e-14: 78.1: 15.89
+	Hs
		681965 AKT1_HUMAN (1-330): 8.38e-132: 403: 23.44		FUBP2_HUMAN (118-416): 2.4e-14: 78.1: 15.89
+	Hs
		1072052 KS6B2_HUMAN (6-405): 5.48e-130: 399: 21.79		PCBP1_HUMAN (476-574): 1.53e-12: 71: 17.17
+	Hs
		1255564 NEK7_HUMAN (3-252): 5.44e-53: 188: 40.23		FUBP2_HUMAN (118-416): 2.4e-14: 78.1: 15.89