Interactor 1: UB2E1 (P51965)
Ubiquitin-conjugating enzyme E2 E1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme E1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme E1) (UbcH6) (Ubiquitin carrier protein E1) (Ubiquitin-protein ligase E1)
Gene: UBE2E1
Interactor 2: MDM2 (Q00987)
E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (Hdm2) (Oncoprotein Mdm2) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2)
Gene: MDM2
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 30017913 |
| Identification Methods | pull down |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | UQ_con~zf-C3HC4_3 |
| Common GO terms | GO:0000209 - protein polyubiquitination GO:0004842 - ubiquitin-protein transferase activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol and 2 others more... |
| Homologous interactions | 14 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
