HitPredict

Interactor 1: UB2E1 (P51965)
Ubiquitin-conjugating enzyme E2 E1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme E1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme E1) (UbcH6) (Ubiquitin carrier protein E1) (Ubiquitin-protein ligase E1)
Gene: UBE2E1

Interactor 2: OTUB1 (Q96FW1)
Ubiquitin thioesterase OTUB1 (EC 3.4.19.12) (Deubiquitinating enzyme OTUB1) (OTU domain-containing ubiquitin aldehyde-binding protein 1) (Otubain-1) (hOTU1) (Ubiquitin-specific-processing protease OTUB1)
Gene: OTUB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.938

The method score is based on:

Property Details
Experiments 28073915, 32049508, 26752685, 33961781, 35927303, 19549727
Identification Methods affinity chromatography technology, pull down, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Peptidase_C65~UQ_con
Common GO terms GO:0005654 - nucleoplasm
GO:0005829 - cytosol
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 193
Hs

1 271
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024