HitPredict

Interactor 1: UB2E1 (P51965)
Ubiquitin-conjugating enzyme E2 E1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme E1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme E1) (UbcH6) (Ubiquitin carrier protein E1) (Ubiquitin-protein ligase E1)
Gene: UBE2E1

Interactor 2: RNF5 (Q99942)
E3 ubiquitin-protein ligase RNF5 (EC 2.3.2.27) (RING finger protein 5) (Ram1 homolog) (HsRma1)
Gene: RNF5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.785

The method score is based on:

Property Details
Experiments 19549727, 14667819
Identification Methods two hybrid, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains UQ_con~zf-C3HC4_3
Common GO terms GO:0004842 - ubiquitin-protein transferase activity
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0070936 - protein K48-linked ubiquitination
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 193
Hs

1 180
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024