HitPredict

Interactor 1: UB2E1 (P51965)
Ubiquitin-conjugating enzyme E2 E1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme E1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme E1) (UbcH6) (Ubiquitin carrier protein E1) (Ubiquitin-protein ligase E1)
Gene: UBE2E1

Interactor 2: RN167 (Q9H6Y7)
E3 ubiquitin-protein ligase RNF167 (EC 2.3.2.27) (RING finger protein 167)
Gene: RNF167

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.928

The method score is based on:

Property Details
Experiments 19690564, 23414517, 33650289, 35114100, 16314844
Identification Methods two hybrid, pull down, two hybrid array, two hybrid fragment pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains UQ_con~zf-RING_2
Common GO terms GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 193
Hs

1 350
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024