HitPredict

Interactor 1: ROA3 (P51991)
Heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3)
Gene: HNRNPA3

Interactor 2: EWS (Q01844)
RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein)
Gene: EWSR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	24999758, 29884807
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 378 Hs			1 656
+	Hs
		162015 HNRDL_HUMAN (20-303): 9.32e-70: 226: 32.30		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		852117 ROA3_HUMAN (1-209): 2.02e-60: 201: 100.00		RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05
+	Hs
		967165 HNRPD_HUMAN (8-299): 1.73e-54: 184: 34.59		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		161976 HNRDL_HUMAN (20-303): 9.32e-70: 226: 32.30		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Hs
		726672 ROA3_HUMAN (1-209): 2.02e-60: 201: 100.00		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Hs
		1271174 ROAA_HUMAN (12-208): 7.23e-36: 135: 38.38		RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05
+	Hs
		726810 HNRPD_HUMAN (8-299): 1.73e-54: 184: 34.59		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Hs
		967387 ROAA_HUMAN (12-208): 7.23e-36: 135: 38.38		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		609978 ROA2_HUMAN (8-126): 3.48e-26: 109: 29.27		RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05
+	Hs
		609816 ROA2_HUMAN (8-126): 3.48e-26: 109: 29.27		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		453508 ROA1_HUMAN (8-116): 5.62e-19: 89.4: 29.20		RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05
+	Sc
		634002 HRP1_YEAST (22-375): 8.12e-55: 190: 28.09		GBP2_YEAST (343-453): 3.82e-16: 83.2: 24.56
+	Hs
		453296 ROA1_HUMAN (8-116): 5.62e-19: 89.4: 29.20		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		727006 ROAA_HUMAN (12-208): 7.23e-36: 135: 38.38		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Dm
		973549 RB97D_DROME (24-211): 1.68e-44: 161: 47.12		Q9VMV5_DROME (3-357): 2.61e-15: 82.2: 12.08
+	Hs
		609735 ROA2_HUMAN (8-126): 3.48e-26: 109: 29.27		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Sc
		376785 PABP_YEAST (6-107): 6.88e-17: 84: 25.24		HRB1_YEAST (241-452): 4.75e-35: 140: 21.76
+	Hs
		453189 ROA1_HUMAN (8-116): 5.62e-19: 89.4: 29.20		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Hs
		726795 PABP4_HUMAN (6-339): 1.18e-16: 83.6: 13.82		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Sc
		376649 PABP_YEAST (6-107): 6.88e-17: 84: 25.24		GBP2_YEAST (343-453): 3.82e-16: 83.2: 24.56