HitPredict

Interactor 1: ROA3 (P51991)
Heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3)
Gene: HNRNPA3

Interactor 2: NCBP1 (Q09161)
Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit)
Gene: NCBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	32960270
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	MIF4G_like~RRM_1, MIF4G_like_2~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:1990904 - ribonucleoprotein complex
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 378 Hs			1 790
+	Hs
		162024 HNRDL_HUMAN (20-303): 9.32e-70: 226: 32.30		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Hs
		998047 HNRPD_HUMAN (8-299): 1.73e-54: 184: 34.59		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Hs
		998167 ROAA_HUMAN (12-208): 7.23e-36: 135: 38.38		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Hs
		609822 ROA2_HUMAN (8-126): 3.48e-26: 109: 29.27		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Hs
		453312 ROA1_HUMAN (8-116): 5.62e-19: 89.4: 29.20		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Hs
		998037 PABP4_HUMAN (6-339): 1.18e-16: 83.6: 13.82		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Hs
		516479 PABP1_HUMAN (6-328): 5.14e-15: 78.6: 12.84		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Hs
		998031 ROA0_HUMAN (17-115): 5.36e-10: 62: 34.34		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Sc
		710248 HRP1_YEAST (22-375): 8.12e-55: 190: 28.09		NCBP1_YEAST (3-693): 2.4e-99: 329: 17.53
+	Sc
		376713 PABP_YEAST (6-107): 6.88e-17: 84: 25.24		NCBP1_YEAST (3-693): 2.4e-99: 329: 17.53