HitPredict

Interactor 1: ROA3 (P51991)
Heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3)
Gene: HNRNPA3

Interactor 2: G3BP1 (Q13283)
Ras GTPase-activating protein-binding protein 1 (G3BP-1) (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent DNA helicase VIII) (hDH VIII) (GAP SH3 domain-binding protein 1)
Gene: G3BP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26777405
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:1990904 - ribonucleoprotein complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 378 Hs			1 466
+	Hs
		1030411 MSI2H_HUMAN (18-364): 1.61e-57: 192: 29.97		G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00
+	Hs
		1030228 HNRPD_HUMAN (8-299): 1.73e-54: 184: 34.59		G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00
+	Hs
		1030438 ROAA_HUMAN (12-208): 7.23e-36: 135: 38.38		G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00
+	Hs
		1048279 HNRPD_HUMAN (8-299): 1.73e-54: 184: 34.59		G3BP2_HUMAN (1-463): 4.59e-76: 248: 58.68
+	Hs
		453329 ROA1_HUMAN (8-116): 5.62e-19: 89.4: 29.20		G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00
+	Hs
		1048071 HNRPD_HUMAN (8-299): 1.73e-54: 184: 34.59		SAFB1_HUMAN (93-439): 7.61e-35: 140: 12.39
+	Hs
		162101 HNRDL_HUMAN (20-303): 9.32e-70: 226: 32.30		CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29
+	Dm
		1249158 Q9VBQ1_DROME (119-239): 7.29e-25: 107: 26.45		Q8SYC0_DROME (23-421): 1.53e-51: 180: 12.69
+	Hs
		201689 MSI1H_HUMAN (19-364): 3.42e-58: 194: 28.33		CELF5_HUMAN (200-456): 2.14e-15: 80.1: 10.86
+	Hs
		852118 ROA3_HUMAN (1-209): 2.02e-60: 201: 100.00		CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29
+	Hs
		201697 MSI1H_HUMAN (19-364): 3.42e-58: 194: 28.33		CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29
+	Hs
		1048160 HNRPD_HUMAN (8-299): 1.73e-54: 184: 34.59		CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29
+	Dm
		822822 RB97D_DROME (24-211): 1.68e-44: 161: 47.12		RB27C_DROME (319-464): 1.03e-12: 71.6: 22.15
+	Hs
		453376 ROA1_HUMAN (8-116): 5.62e-19: 89.4: 29.20		SAFB1_HUMAN (93-439): 7.61e-35: 140: 12.39
+	Hs
		1272085 ROAA_HUMAN (12-208): 7.23e-36: 135: 38.38		CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29
+	Dm
		1213098 Q8IMS8_DROME (119-239): 2.9e-25: 109: 26.45		Q8IP90_DROME (331-422): 7.57e-15: 79.3: 19.39
+	Hs
		609979 ROA2_HUMAN (8-126): 3.48e-26: 109: 29.27		CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29
+	Dm
		822820 RB87F_DROME (1-117): 3.52e-24: 104: 25.62		RB27C_DROME (319-464): 1.03e-12: 71.6: 22.15
+	Dm
		432486 ROA1_DROME (110-211): 6.21e-21: 94.8: 28.43		RB27C_DROME (319-464): 1.03e-12: 71.6: 22.15
+	Hs
		311334 ROA1_HUMAN (8-116): 5.62e-19: 89.4: 29.20		CELF2_HUMAN (318-402): 4.48e-12: 70: 17.78