HitPredict

Interactor 1: ROA3 (P51991)
Heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3)
Gene: HNRNPA3

Interactor 2: ELAV1 (Q15717)
ELAV-like protein 1 (Hu-antigen R) (HuR)
Gene: ELAVL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0003730 - mRNA 3'-UTR binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:1990904 - ribonucleoprotein complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 378 Hs			1 326
+	Hs
		162059 HNRDL_HUMAN (20-303): 9.32e-70: 226: 32.30		ELAV1_HUMAN (1-326): 8.27e-90: 273: 100.00
+	Hs
		1048074 HNRPD_HUMAN (8-299): 1.73e-54: 184: 34.59		ELAV1_HUMAN (1-326): 8.27e-90: 273: 100.00
+	Hs
		1077470 ROAA_HUMAN (12-208): 7.23e-36: 135: 38.38		ELAV1_HUMAN (1-326): 8.27e-90: 273: 100.00
+	Hs
		162035 HNRDL_HUMAN (20-303): 9.32e-70: 226: 32.30		PABP4_HUMAN (6-240): 1.05e-46: 168: 21.34
+	Hs
		609883 ROA2_HUMAN (8-126): 3.48e-26: 109: 29.27		ELAV1_HUMAN (1-326): 8.27e-90: 273: 100.00
+	Hs
		609862 ROA2_HUMAN (8-126): 3.48e-26: 109: 29.27		ELAV3_HUMAN (1-326): 4.41e-84: 259: 62.82
+	Hs
		453381 ROA1_HUMAN (8-116): 5.62e-19: 89.4: 29.20		ELAV1_HUMAN (1-326): 8.27e-90: 273: 100.00
+	Dm
		562815 Q8IMS8_DROME (119-239): 2.9e-25: 109: 26.45		ELAV_DROME (2-325): 2.03e-72: 233: 45.61
+	Dm
		562817 Q9VBQ1_DROME (119-239): 7.29e-25: 107: 26.45		ELAV_DROME (2-325): 2.03e-72: 233: 45.61
+	Hs
		161948 HNRDL_HUMAN (20-303): 9.32e-70: 226: 32.30		PABP1_HUMAN (234-325): 2.15e-20: 93.5: 19.57
+	Hs
		516424 ROA3_HUMAN (1-209): 2.02e-60: 201: 100.00		PABP1_HUMAN (234-325): 2.15e-20: 93.5: 19.57
+	Dm
		582596 RB87F_DROME (1-117): 3.52e-24: 104: 25.62		SXL_DROME (1-199): 2.37e-54: 182: 43.72
+	Hs
		516511 HNRPD_HUMAN (8-299): 1.73e-54: 184: 34.59		PABP1_HUMAN (234-325): 2.15e-20: 93.5: 19.57
+	Hs
		453331 ROA1_HUMAN (8-116): 5.62e-19: 89.4: 29.20		PABP4_HUMAN (6-240): 1.05e-46: 168: 21.34
+	Zm
		8143 A0A1D6ELH4_MAIZE (6-345): 1.09e-19: 92.5: 14.37		A0A1D6ELH4_MAIZE (6-238): 1.42e-44: 162: 23.11
+	Hs
		1020319 ROAA_HUMAN (12-208): 7.23e-36: 135: 38.38		ELAV2_HUMAN (212-322): 4.72e-22: 97: 25.23
+	Hs
		516663 ROAA_HUMAN (12-208): 7.23e-36: 135: 38.38		PABP1_HUMAN (234-325): 2.15e-20: 93.5: 19.57
+	Hs
		609833 ROA2_HUMAN (8-126): 3.48e-26: 109: 29.27		ELAV2_HUMAN (212-322): 4.72e-22: 97: 25.23
+	Hs
		516358 ROA2_HUMAN (8-126): 3.48e-26: 109: 29.27		PABP1_HUMAN (234-325): 2.15e-20: 93.5: 19.57
+	Hs
		453107 ROA1_HUMAN (8-116): 5.62e-19: 89.4: 29.20		PABP1_HUMAN (234-325): 2.15e-20: 93.5: 19.57