HitPredict

Interactor 1: ROA3 (P51991)
Heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3)
Gene: HNRNPA3

Interactor 2: PSPC1 (Q8WXF1)
Paraspeckle component 1 (Paraspeckle protein 1)
Gene: PSPC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	NOPS~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 378 Hs			1 523
+	Hs
		162097 HNRDL_HUMAN (20-303): 9.32e-70: 226: 32.30		PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00
+	Hs
		161948 HNRDL_HUMAN (20-303): 9.32e-70: 226: 32.30		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		162056 HNRDL_HUMAN (20-303): 9.32e-70: 226: 32.30		NONO_HUMAN (50-523): 4.22e-68: 228: 57.60
+	Hs
		516424 ROA3_HUMAN (1-209): 2.02e-60: 201: 100.00		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		516511 HNRPD_HUMAN (8-299): 1.73e-54: 184: 34.59		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		852134 ROA3_HUMAN (1-209): 2.02e-60: 201: 100.00		PABP5_HUMAN (86-416): 1.38e-52: 184: 16.90
+	Hs
		516663 ROAA_HUMAN (12-208): 7.23e-36: 135: 38.38		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Sc
		376993 HRP1_YEAST (22-375): 8.12e-55: 190: 28.09		PABP_YEAST (4-373): 1.42e-48: 178: 14.85
+	Hs
		516358 ROA2_HUMAN (8-126): 3.48e-26: 109: 29.27		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		162035 HNRDL_HUMAN (20-303): 9.32e-70: 226: 32.30		PABP4_HUMAN (3-149): 2.52e-27: 118: 18.83
+	Hs
		609715 ROA2_HUMAN (8-126): 3.48e-26: 109: 29.27		SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14
+	Hs
		162059 HNRDL_HUMAN (20-303): 9.32e-70: 226: 32.30		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Hs
		852068 ROA3_HUMAN (1-209): 2.02e-60: 201: 100.00		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Hs
		1048074 HNRPD_HUMAN (8-299): 1.73e-54: 184: 34.59		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Hs
		201707 MSI1H_HUMAN (19-364): 3.42e-58: 194: 28.33		RBM4B_HUMAN (83-190): 4.07e-09: 60.5: 33.04
+	Hs
		1048209 HNRPD_HUMAN (8-299): 1.73e-54: 184: 34.59		RBM4_HUMAN (83-190): 4.98e-09: 60.1: 32.14
+	Hs
		1020319 ROAA_HUMAN (12-208): 7.23e-36: 135: 38.38		ELAV2_HUMAN (84-156): 1.29e-13: 74.1: 31.65
+	Hs
		1077470 ROAA_HUMAN (12-208): 7.23e-36: 135: 38.38		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Hs
		609833 ROA2_HUMAN (8-126): 3.48e-26: 109: 29.27		ELAV2_HUMAN (84-156): 1.29e-13: 74.1: 31.65
+	Dm
		562815 Q8IMS8_DROME (119-239): 2.9e-25: 109: 26.45		ELAV_DROME (84-157): 1.77e-12: 71.4: 27.50