HitPredict

Interactor 1: ROA3 (P51991)
Heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3)
Gene: HNRNPA3

Interactor 2: FBXW7 (Q969H0)
F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4)
Gene: FBXW7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33658012
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 378 Hs			1 707
+	Hs
		1048172 HNRPD_HUMAN (8-299): 1.73e-54: 184: 34.59		FBXW7_HUMAN (1-707): 0: 571: 100.00
+	Hs
		609988 ROA2_HUMAN (8-126): 3.48e-26: 109: 29.27		FBXW7_HUMAN (1-707): 0: 571: 100.00
+	Hs
		453519 ROA1_HUMAN (8-116): 5.62e-19: 89.4: 29.20		FBXW7_HUMAN (1-707): 0: 571: 100.00
+	Hs
		162000 HNRDL_HUMAN (20-303): 9.32e-70: 226: 32.30		WDR5_HUMAN (570-706): 2.64e-27: 115: 23.02
+	Hs
		852006 ROA3_HUMAN (1-209): 2.02e-60: 201: 100.00		WDR5_HUMAN (570-706): 2.64e-27: 115: 23.02
+	Hs
		903216 HNRPD_HUMAN (8-299): 1.73e-54: 184: 34.59		WDR5_HUMAN (570-706): 2.64e-27: 115: 23.02
+	Hs
		162186 HNRDL_HUMAN (20-303): 9.32e-70: 226: 32.30		FBW1A_HUMAN (614-705): 2.9e-12: 72: 26.09
+	Hs
		162182 HNRDL_HUMAN (20-303): 9.32e-70: 226: 32.30		FBW1B_HUMAN (614-705): 7.05e-12: 70.5: 25.00
+	Hs
		852208 ROA3_HUMAN (1-209): 2.02e-60: 201: 100.00		FBW1A_HUMAN (614-705): 2.9e-12: 72: 26.09
+	Hs
		852199 ROA3_HUMAN (1-209): 2.02e-60: 201: 100.00		FBW1B_HUMAN (614-705): 7.05e-12: 70.5: 25.00
+	Hs
		1288227 MSI2H_HUMAN (18-364): 1.61e-57: 192: 29.97		FBW1A_HUMAN (614-705): 2.9e-12: 72: 26.09
+	Hs
		1048285 HNRPD_HUMAN (8-299): 1.73e-54: 184: 34.59		FBW1A_HUMAN (614-705): 2.9e-12: 72: 26.09
+	Hs
		1048270 HNRPD_HUMAN (8-299): 1.73e-54: 184: 34.59		FBW1B_HUMAN (614-705): 7.05e-12: 70.5: 25.00
+	Hs
		903463 ROAA_HUMAN (12-208): 7.23e-36: 135: 38.38		WDR5_HUMAN (570-706): 2.64e-27: 115: 23.02
+	Hs
		609790 ROA2_HUMAN (8-126): 3.48e-26: 109: 29.27		WDR5_HUMAN (570-706): 2.64e-27: 115: 23.02
+	Hs
		1306046 ROAA_HUMAN (12-208): 7.23e-36: 135: 38.38		FBW1A_HUMAN (614-705): 2.9e-12: 72: 26.09
+	Hs
		1306041 ROAA_HUMAN (12-208): 7.23e-36: 135: 38.38		FBW1B_HUMAN (614-705): 7.05e-12: 70.5: 25.00
+	Hs
		453251 ROA1_HUMAN (8-116): 5.62e-19: 89.4: 29.20		WDR5_HUMAN (570-706): 2.64e-27: 115: 23.02
+	Hs
		610117 ROA2_HUMAN (8-126): 3.48e-26: 109: 29.27		FBW1A_HUMAN (614-705): 2.9e-12: 72: 26.09
+	Hs
		610101 ROA2_HUMAN (8-126): 3.48e-26: 109: 29.27		FBW1B_HUMAN (614-705): 7.05e-12: 70.5: 25.00