HitPredict

Interactor 1: YPT32 (P51996)
GTP-binding protein YPT32/YPT11 (Rab GTPase YPT32)
Gene: YPT32

Interactor 2: GYP1 (Q08484)
GTPase-activating protein GYP1 (GAP for YPT1)
Gene: GYP1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.807

Property	Details
Experiments	19666511, 24194547
Identification Methods	pull down, two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RabGAP-TBC~Ras
Common GO terms	GO:0005794 - Golgi apparatus GO:0016192 - vesicle-mediated transport
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 222 Sc			1 637
+	Sc
		750763 YPT31_YEAST (1-222): 1.28e-87: 259: 80.72		GYP1_YEAST (1-637): 1.25e-172: 507: 100.00
+	Dm
		185563 RAB2_DROME (10-222): 8.16e-101: 292: 41.59		Q9VKV6_DROME (8-575): 1.21e-80: 270: 13.26
+	Hs
		918951 RAB1A_HUMAN (1-222): 2.65e-87: 258: 41.44		TBC17_HUMAN (3-577): 1.03e-87: 288: 15.64
+	Os
		772871 RIC2_ORYSJ (1-222): 7.87e-85: 252: 56.50		Q5SMT0_ORYSJ (65-563): 1.13e-86: 286: 16.37
+	Hs
		914391 RB11A_HUMAN (4-221): 1.75e-84: 251: 58.72		TB22B_HUMAN (101-546): 2.21e-88: 285: 30.85
+	Hs
		1079972 RB11B_HUMAN (4-222): 2.1e-84: 251: 58.90		TBC14_HUMAN (16-565): 1.54e-81: 273: 13.63
+	Hs
		914423 RB11A_HUMAN (4-221): 1.75e-84: 251: 58.72		TBC14_HUMAN (16-565): 1.54e-81: 273: 13.63
+	Dm
		185710 O18335_DROME (4-222): 3.93e-83: 247: 59.82		Q9VPL5_DROME (33-585): 1.47e-82: 276: 17.49
+	Hs
		233036 RB11A_HUMAN (4-221): 1.75e-84: 251: 58.72		TBC12_HUMAN (41-565): 1.33e-80: 272: 14.92
+	Hs
		232698 RAB2B_HUMAN (10-222): 1.43e-84: 251: 39.25		TBCD4_HUMAN (8-628): 3e-77: 270: 15.32
+	Hs
		321281 RB11A_HUMAN (4-221): 1.75e-84: 251: 58.72		TBCD8_HUMAN (110-637): 1.37e-73: 258: 11.97
+	Hs
		914176 RB11A_HUMAN (4-221): 1.75e-84: 251: 58.72		TBCD1_HUMAN (56-627): 1.06e-72: 256: 15.20
+	Hs
		914259 RB11A_HUMAN (4-221): 1.75e-84: 251: 58.72		TBCD5_HUMAN (198-619): 1.03e-70: 246: 13.53
+	Hs
		884602 RAB25_HUMAN (9-202): 8.48e-69: 211: 54.64		TB22B_HUMAN (101-546): 2.21e-88: 285: 30.85
+	Hs
		884545 RAB25_HUMAN (9-202): 8.48e-69: 211: 54.64		TBC15_HUMAN (128-574): 2.24e-82: 275: 18.03
+	Dm
		1197045 Q86BK8_DROME (8-214): 5.1e-61: 192: 47.34		Q9VPL5_DROME (33-585): 1.47e-82: 276: 17.49
+	Hs
		884554 RAB25_HUMAN (9-202): 8.48e-69: 211: 54.64		TBCD5_HUMAN (198-619): 1.03e-70: 246: 13.53
+	Hs
		195603 RAB2B_HUMAN (10-222): 1.43e-84: 251: 39.25		SGSM2_HUMAN (334-516): 1.67e-26: 117: 17.39