HitPredict

Interactor 1: KCJ12 (P52188)
ATP-sensitive inward rectifier potassium channel 12 (Inward rectifier K(+) channel Kir2.2) (IRK-2) (Potassium channel, inwardly rectifying subfamily J member 12)
Gene: Kcnj12

Interactor 2: DLG1 (Q62696)
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97)
Gene: DLG1

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	11181181, 15024025
Identification Methods	pull down, anti bait coimmunoprecipitation
Interaction Type	physical association, association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030165 - PDZ domain binding GO:0030315 - T-tubule GO:0030425 - dendrite GO:0043025 - neuronal cell body
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 427 Rn			1 911
+	Hs
		1021490 KCJ12_HUMAN (1-427): 0: 741: 96.07		DLG1_HUMAN (1-911): 0: 705: 92.22
+	Hs
		80982 KCJ18_HUMAN (1-427): 0: 732: 94.69		DLG1_HUMAN (1-911): 0: 705: 92.22
+	Rn
		1144015 KCNJ2_RAT (6-427): 0: 695: 70.82		DLG1_RAT (1-911): 0: 732: 100.00
+	Hs
		929764 KCNJ2_HUMAN (6-427): 0: 699: 70.82		DLG1_HUMAN (1-911): 0: 705: 92.22
+	Rn
		852399 KCJ12_RAT (1-427): 0: 747: 100.00		DLG3_RAT (190-911): 0: 591: 69.43
+	Hs
		1054724 KCJ12_HUMAN (1-427): 0: 741: 96.07		DLG3_HUMAN (107-911): 0: 586: 62.56
+	Hs
		1054729 KCJ12_HUMAN (1-427): 0: 741: 96.07		PALS2_HUMAN (337-906): 4.94e-112: 356: 21.20
+	Rn
		852398 KCJ12_RAT (1-427): 0: 747: 100.00		CSKP_RAT (12-429): 5.46e-26: 117: 12.38
+	Rn
		677769 KCJ12_RAT (1-427): 0: 747: 100.00		DLG4_RAT (157-366): 6.44e-24: 110: 24.17
+	Hs
		159210 KCJ12_HUMAN (1-427): 0: 741: 96.07		CSKP_HUMAN (12-429): 5.61e-25: 114: 12.10
+	Rn
		852400 KCJ12_RAT (1-427): 0: 747: 100.00		DLG2_RAT (376-769): 1.37e-22: 106: 19.75
+	Hs
		942342 KCJ12_HUMAN (1-427): 0: 741: 96.07		DLG4_HUMAN (157-406): 3.82e-24: 111: 22.71
+	Hs
		1049947 KCJ12_HUMAN (1-427): 0: 741: 96.07		SCRIB_HUMAN (217-395): 5.26e-23: 108: 41.18
+	Hs
		1054723 KCJ12_HUMAN (1-427): 0: 741: 96.07		DLG2_HUMAN (376-769): 9.42e-23: 106: 19.75
+	Hs
		929762 KCNJ2_HUMAN (6-427): 0: 699: 70.82		DLG4_HUMAN (157-406): 3.82e-24: 111: 22.71
+	Hs
		929767 KCNJ2_HUMAN (6-427): 0: 699: 70.82		SCRIB_HUMAN (217-395): 5.26e-23: 108: 41.18
+	Rn
		1144360 KCNJ2_RAT (6-427): 0: 695: 70.82		DLG2_RAT (376-769): 1.37e-22: 106: 19.75
+	Hs
		159173 KCNJ4_HUMAN (31-427): 0: 571: 62.81		CSKP_HUMAN (12-429): 5.61e-25: 114: 12.10
+	Mm
		852403 KCNJ4_MOUSE (32-427): 0: 574: 62.73		DLG4_MOUSE (157-406): 3.36e-24: 111: 22.71
+	Hs
		816146 KCNJ4_HUMAN (31-427): 0: 571: 62.81		DLG4_HUMAN (157-406): 3.82e-24: 111: 22.71