HitPredict

Interactor 1: KCJ12 (P52188)
ATP-sensitive inward rectifier potassium channel 12 (Inward rectifier K(+) channel Kir2.2) (IRK-2) (Potassium channel, inwardly rectifying subfamily J member 12)
Gene: Kcnj12

Interactor 2: DLG3 (Q62936)
Disks large homolog 3 (PSD-95/SAP90-related protein 1) (Synapse-associated protein 102) (SAP-102) (SAP102)
Gene: DLG3

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	15024025
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030165 - PDZ domain binding GO:0043025 - neuronal cell body
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 427 Rn			1 849
+	Hs
		1054724 KCJ12_HUMAN (1-427): 0: 741: 96.07		DLG3_HUMAN (1-849): 0: 680: 95.29
+	Hs
		1021490 KCJ12_HUMAN (1-427): 0: 741: 96.07		DLG1_HUMAN (4-849): 0: 589: 62.37
+	Hs
		80982 KCJ18_HUMAN (1-427): 0: 732: 94.69		DLG1_HUMAN (4-849): 0: 589: 62.37
+	Rn
		677769 KCJ12_RAT (1-427): 0: 747: 100.00		DLG4_RAT (100-849): 0: 572: 62.82
+	Rn
		852397 KCJ12_RAT (1-427): 0: 747: 100.00		DLG1_RAT (4-849): 0: 570: 60.38
+	Hs
		942342 KCJ12_HUMAN (1-427): 0: 741: 96.07		DLG4_HUMAN (100-849): 0: 572: 62.95
+	Hs
		929764 KCNJ2_HUMAN (6-427): 0: 699: 70.82		DLG1_HUMAN (4-849): 0: 589: 62.37
+	Hs
		929762 KCNJ2_HUMAN (6-427): 0: 699: 70.82		DLG4_HUMAN (100-849): 0: 572: 62.95
+	Rn
		1144015 KCNJ2_RAT (6-427): 0: 695: 70.82		DLG1_RAT (4-849): 0: 570: 60.38
+	Hs
		816147 KCNJ4_HUMAN (31-427): 0: 571: 62.81		DLG1_HUMAN (4-849): 0: 589: 62.37
+	Mm
		852403 KCNJ4_MOUSE (32-427): 0: 574: 62.73		DLG4_MOUSE (100-849): 0: 572: 62.95
+	Hs
		816146 KCNJ4_HUMAN (31-427): 0: 571: 62.81		DLG4_HUMAN (100-849): 0: 572: 62.95
+	Hs
		1054729 KCJ12_HUMAN (1-427): 0: 741: 96.07		PALS2_HUMAN (298-844): 2.46e-105: 337: 23.06
+	Rn
		852400 KCJ12_RAT (1-427): 0: 747: 100.00		DLG2_RAT (315-691): 6.7e-22: 103: 17.83
+	Rn
		852398 KCJ12_RAT (1-427): 0: 747: 100.00		CSKP_RAT (45-371): 1.78e-20: 99.1: 10.42
+	Hs
		1054723 KCJ12_HUMAN (1-427): 0: 741: 96.07		DLG2_HUMAN (315-690): 3.67e-21: 101: 17.88
+	Hs
		159210 KCJ12_HUMAN (1-427): 0: 741: 96.07		CSKP_HUMAN (45-371): 8.4e-20: 97.2: 11.49
+	Rn
		1144360 KCNJ2_RAT (6-427): 0: 695: 70.82		DLG2_RAT (315-691): 6.7e-22: 103: 17.83
+	Hs
		816150 KCNJ4_HUMAN (31-427): 0: 571: 62.81		DLG2_HUMAN (315-690): 3.67e-21: 101: 17.88
+	Hs
		159173 KCNJ4_HUMAN (31-427): 0: 571: 62.81		CSKP_HUMAN (45-371): 8.4e-20: 97.2: 11.49