HitPredict

Interactor 1: KCJ12 (P52188)
ATP-sensitive inward rectifier potassium channel 12 (Inward rectifier K(+) channel Kir2.2) (IRK-2) (Potassium channel, inwardly rectifying subfamily J member 12)
Gene: Kcnj12

Interactor 2: DLG2 (Q63622)
Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93)
Gene: DLG2

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	15024025
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0030165 - PDZ domain binding GO:0030425 - dendrite GO:0043025 - neuronal cell body
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 427 Rn			1 852
+	Hs
		1054723 KCJ12_HUMAN (1-427): 0: 741: 96.07		DLG2_HUMAN (1-852): 0: 725: 94.94
+	Rn
		1144360 KCNJ2_RAT (6-427): 0: 695: 70.82		DLG2_RAT (1-852): 0: 751: 100.00
+	Hs
		816150 KCNJ4_HUMAN (31-427): 0: 571: 62.81		DLG2_HUMAN (1-852): 0: 725: 94.94
+	Hs
		1021490 KCJ12_HUMAN (1-427): 0: 741: 96.07		DLG1_HUMAN (7-852): 4.33e-169: 515: 53.34
+	Rn
		852397 KCJ12_RAT (1-427): 0: 747: 100.00		DLG1_RAT (9-852): 4.45e-164: 502: 51.95
+	Hs
		80982 KCJ18_HUMAN (1-427): 0: 732: 94.69		DLG1_HUMAN (7-852): 4.33e-169: 515: 53.34
+	Hs
		929764 KCNJ2_HUMAN (6-427): 0: 699: 70.82		DLG1_HUMAN (7-852): 4.33e-169: 515: 53.34
+	Rn
		1144015 KCNJ2_RAT (6-427): 0: 695: 70.82		DLG1_RAT (9-852): 4.45e-164: 502: 51.95
+	Hs
		816147 KCNJ4_HUMAN (31-427): 0: 571: 62.81		DLG1_HUMAN (7-852): 4.33e-169: 515: 53.34
+	Rn
		677769 KCJ12_RAT (1-427): 0: 747: 100.00		DLG4_RAT (4-419): 7.48e-31: 131: 17.37
+	Rn
		852399 KCJ12_RAT (1-427): 0: 747: 100.00		DLG3_RAT (10-391): 7.38e-29: 126: 17.87
+	Hs
		942342 KCJ12_HUMAN (1-427): 0: 741: 96.07		DLG4_HUMAN (4-419): 6.5e-31: 132: 17.37
+	Hs
		1054724 KCJ12_HUMAN (1-427): 0: 741: 96.07		DLG3_HUMAN (10-366): 1.42e-29: 128: 16.80
+	Rn
		852398 KCJ12_RAT (1-427): 0: 747: 100.00		CSKP_RAT (68-297): 1.94e-20: 99.1: 11.02
+	Hs
		159210 KCJ12_HUMAN (1-427): 0: 741: 96.07		CSKP_HUMAN (68-297): 4.46e-20: 97.9: 12.50
+	Hs
		929762 KCNJ2_HUMAN (6-427): 0: 699: 70.82		DLG4_HUMAN (4-419): 6.5e-31: 132: 17.37
+	Hs
		1054729 KCJ12_HUMAN (1-427): 0: 741: 96.07		PALS2_HUMAN (7-233): 2.25e-14: 79.1: 16.73
+	Mm
		852403 KCNJ4_MOUSE (32-427): 0: 574: 62.73		DLG4_MOUSE (4-419): 3.42e-31: 132: 17.37
+	Hs
		816146 KCNJ4_HUMAN (31-427): 0: 571: 62.81		DLG4_HUMAN (4-419): 6.5e-31: 132: 17.37
+	Hs
		159173 KCNJ4_HUMAN (31-427): 0: 571: 62.81		CSKP_HUMAN (68-297): 4.46e-20: 97.9: 12.50