HitPredict

Interactor 1: KCJ12 (P52188)
ATP-sensitive inward rectifier potassium channel 12 (Inward rectifier K(+) channel Kir2.2) (IRK-2) (Potassium channel, inwardly rectifying subfamily J member 12)
Gene: Kcnj12

Interactor 2: LIN7A (Q9Z250)
Protein lin-7 homolog A (Lin-7A) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1)
Gene: LIN7A

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	15024025
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane GO:0030165 - PDZ domain binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 427 Rn			1 232
+	Hs
		158284 KCJ12_HUMAN (1-427): 0: 741: 96.07		LIN7A_HUMAN (1-232): 1.22e-60: 192: 97.85
+	Rn
		852401 KCJ12_RAT (1-427): 0: 747: 100.00		LIN7C_RAT (17-212): 6.88e-53: 170: 78.57
+	Hs
		1054726 KCJ12_HUMAN (1-427): 0: 741: 96.07		LIN7B_HUMAN (17-217): 1.08e-53: 173: 76.62
+	Hs
		1054728 KCJ12_HUMAN (1-427): 0: 741: 96.07		LIN7C_HUMAN (17-212): 6.88e-53: 170: 78.57
+	Hs
		1033833 KCJ12_HUMAN (1-427): 0: 741: 96.07		SNTA1_HUMAN (28-232): 1.92e-36: 135: 21.80
+	Hs
		1046429 KCJ12_HUMAN (1-427): 0: 741: 96.07		SNTB1_HUMAN (66-231): 5.62e-33: 126: 23.35
+	Hs
		1033871 KCJ12_HUMAN (1-427): 0: 741: 96.07		SNTB2_HUMAN (98-194): 1.73e-31: 122: 36.08
+	Rn
		852400 KCJ12_RAT (1-427): 0: 747: 100.00		DLG2_RAT (9-231): 1.44e-28: 114: 19.01
+	Hs
		1054723 KCJ12_HUMAN (1-427): 0: 741: 96.07		DLG2_HUMAN (9-231): 2.57e-28: 114: 18.60
+	Rn
		677769 KCJ12_RAT (1-427): 0: 747: 100.00		DLG4_RAT (29-230): 1.58e-26: 108: 20.00
+	Hs
		942342 KCJ12_HUMAN (1-427): 0: 741: 96.07		DLG4_HUMAN (29-230): 1.75e-26: 108: 20.00
+	Rn
		852397 KCJ12_RAT (1-427): 0: 747: 100.00		DLG1_RAT (109-184): 2.91e-22: 96.8: 41.98
+	Hs
		1021490 KCJ12_HUMAN (1-427): 0: 741: 96.07		DLG1_HUMAN (109-186): 1.2e-22: 97.9: 42.17
+	Rn
		852399 KCJ12_RAT (1-427): 0: 747: 100.00		DLG3_RAT (88-179): 5.16e-20: 90.3: 34.02
+	Hs
		929765 KCNJ2_HUMAN (6-427): 0: 699: 70.82		SNTA1_HUMAN (28-232): 1.92e-36: 135: 21.80
+	Hs
		1054724 KCJ12_HUMAN (1-427): 0: 741: 96.07		DLG3_HUMAN (41-179): 1.2e-19: 89.2: 24.18
+	Hs
		80982 KCJ18_HUMAN (1-427): 0: 732: 94.69		DLG1_HUMAN (109-186): 1.2e-22: 97.9: 42.17
+	Hs
		929762 KCNJ2_HUMAN (6-427): 0: 699: 70.82		DLG4_HUMAN (29-230): 1.75e-26: 108: 20.00
+	Hs
		929764 KCNJ2_HUMAN (6-427): 0: 699: 70.82		DLG1_HUMAN (109-186): 1.2e-22: 97.9: 42.17
+	Rn
		1144015 KCNJ2_RAT (6-427): 0: 695: 70.82		DLG1_RAT (109-184): 2.91e-22: 96.8: 41.98