HitPredict

Interactor 1: KCNJ4 (P52189)
Inward rectifier potassium channel 4 (Inward rectifier K(+) channel Kir2.3) (IRK-3) (Potassium channel, inwardly rectifying subfamily J member 4)
Gene: KCNJ4

Interactor 2: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	28671696, 19455133
Identification Methods	anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030425 - dendrite GO:0045211 - postsynaptic membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 445 Mm			1 724
+	Hs
		816146 KCNJ4_HUMAN (1-445): 0: 680: 96.19		DLG4_HUMAN (1-724): 0: 671: 99.59
+	Mm
		1143540 Q9QYK8_MOUSE (9-439): 0: 666: 99.30		DLG4_MOUSE (1-724): 0: 671: 100.00
+	Hs
		942342 KCJ12_HUMAN (7-445): 0: 659: 63.78		DLG4_HUMAN (1-724): 0: 671: 99.59
+	Hs
		929762 KCNJ2_HUMAN (7-445): 0: 653: 60.00		DLG4_HUMAN (1-724): 0: 671: 99.59
+	Rn
		677769 KCJ12_RAT (7-445): 0: 640: 63.33		DLG4_RAT (1-724): 0: 671: 99.45
+	Hs
		1054724 KCJ12_HUMAN (7-445): 0: 659: 63.78		DLG3_HUMAN (28-724): 0: 600: 64.92
+	Hs
		816147 KCNJ4_HUMAN (1-445): 0: 680: 96.19		DLG1_HUMAN (28-724): 0: 576: 72.79
+	Hs
		1021490 KCJ12_HUMAN (7-445): 0: 659: 63.78		DLG1_HUMAN (28-724): 0: 576: 72.79
+	Hs
		929764 KCNJ2_HUMAN (7-445): 0: 653: 60.00		DLG1_HUMAN (28-724): 0: 576: 72.79
+	Hs
		80982 KCJ18_HUMAN (7-445): 0: 652: 63.33		DLG1_HUMAN (28-724): 0: 576: 72.79
+	Rn
		1144015 KCNJ2_RAT (7-445): 0: 650: 60.23		DLG1_RAT (8-724): 0: 564: 66.98
+	Hs
		816149 KCNJ4_HUMAN (1-445): 0: 680: 96.19		SCRIB_HUMAN (58-243): 7.53e-25: 113: 40.72
+	Hs
		159173 KCNJ4_HUMAN (1-445): 0: 680: 96.19		CSKP_HUMAN (6-381): 1.53e-20: 99: 14.43
+	Hs
		1049947 KCJ12_HUMAN (7-445): 0: 659: 63.78		SCRIB_HUMAN (58-243): 7.53e-25: 113: 40.72
+	Hs
		816150 KCNJ4_HUMAN (1-445): 0: 680: 96.19		DLG2_HUMAN (234-580): 8.36e-18: 90.1: 19.55
+	Hs
		929767 KCNJ2_HUMAN (7-445): 0: 653: 60.00		SCRIB_HUMAN (58-243): 7.53e-25: 113: 40.72
+	Hs
		159210 KCJ12_HUMAN (7-445): 0: 659: 63.78		CSKP_HUMAN (6-381): 1.53e-20: 99: 14.43
+	Hs
		1054723 KCJ12_HUMAN (7-445): 0: 659: 63.78		DLG2_HUMAN (234-580): 8.36e-18: 90.1: 19.55
+	Rn
		1144360 KCNJ2_RAT (7-445): 0: 650: 60.23		DLG2_RAT (234-580): 2.32e-17: 88.6: 19.55
+	Hs
		1054729 KCJ12_HUMAN (7-445): 0: 659: 63.78		PALS2_HUMAN (22-193): 2.91e-13: 75.1: 15.52