HitPredict

Interactor 1: RND2 (P52198)
Rho-related GTP-binding protein RhoN (Rho family GTPase 2) (Rho-related GTP-binding protein Rho7) (Rnd2)
Gene: RND2

Interactor 2: EPHB4 (P54760)
Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)
Gene: EPHB4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~fn3
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 227 Hs			1 987
+	Hs
		872519 RND3_HUMAN (4-227): 3.64e-100: 292: 64.00		EPHB4_HUMAN (1-987): 0: 1122: 100.00
+	Hs
		872558 RND1_HUMAN (6-227): 1.9e-83: 249: 53.15		EPHB4_HUMAN (1-987): 0: 1122: 100.00
+	Hs
		872518 RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03		EPHB4_HUMAN (1-987): 0: 1122: 100.00
+	Hs
		436224 RHOC_HUMAN (9-193): 3.15e-81: 242: 48.11		EPHB4_HUMAN (1-987): 0: 1122: 100.00
+	Hs
		872522 RAC1_HUMAN (8-194): 1.25e-78: 235: 42.25		EPHB4_HUMAN (1-987): 0: 1122: 100.00
+	Hs
		1072566 RND1_HUMAN (6-227): 1.9e-83: 249: 53.15		EPHA7_HUMAN (3-981): 0: 1100: 48.64
+	Hs
		900497 RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03		EPHA7_HUMAN (3-981): 0: 1100: 48.64
+	Hs
		436317 RHOC_HUMAN (9-193): 3.15e-81: 242: 48.11		EPHA7_HUMAN (3-981): 0: 1100: 48.64
+	Hs
		436223 RHOC_HUMAN (9-193): 3.15e-81: 242: 48.11		EPHA5_HUMAN (1-978): 0: 1099: 47.77
+	Hs
		925297 RAC1_HUMAN (8-194): 1.25e-78: 235: 42.25		EPHA7_HUMAN (3-981): 0: 1100: 48.64
+	Hs
		872423 RAC1_HUMAN (8-194): 1.25e-78: 235: 42.25		EPHA5_HUMAN (1-978): 0: 1099: 47.77
+	Hs
		665177 RND2_HUMAN (1-227): 7.71e-110: 316: 100.00		EPHA2_HUMAN (15-974): 0: 1016: 44.82
+	Hs
		665195 RND3_HUMAN (4-227): 3.64e-100: 292: 64.00		EPHA2_HUMAN (15-974): 0: 1016: 44.82
+	Hs
		665301 RND1_HUMAN (6-227): 1.9e-83: 249: 53.15		EPHA2_HUMAN (15-974): 0: 1016: 44.82
+	Hs
		665194 RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03		EPHA2_HUMAN (15-974): 0: 1016: 44.82
+	Hs
		436169 RHOC_HUMAN (9-193): 3.15e-81: 242: 48.11		EPHA2_HUMAN (15-974): 0: 1016: 44.82
+	Hs
		665201 RAC1_HUMAN (8-194): 1.25e-78: 235: 42.25		EPHA2_HUMAN (15-974): 0: 1016: 44.82
+	Rn
		71354 B2RYP0_RAT (5-197): 3.28e-96: 280: 48.19		INSR_RAT (380-879): 6.3e-136: 444: 30.43
+	Rn
		102471 G3V6H0_RAT (2-224): 3.11e-78: 235: 20.09		INSR_RAT (380-879): 6.3e-136: 444: 30.43
+	Hs
		925220 RAC1_HUMAN (8-194): 1.25e-78: 235: 42.25		FAK1_HUMAN (595-878): 1.01e-61: 230: 41.55