HitPredict

Interactor 1: RND2 (P52198)
Rho-related GTP-binding protein RhoN (Rho family GTPase 2) (Rho-related GTP-binding protein Rho7) (Rnd2)
Gene: RND2

Interactor 2: S12A2 (P55011)
Solute carrier family 12 member 2 (Basolateral Na-K-Cl symporter) (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2)
Gene: SLC12A2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 227 Hs			1 1212
+	Hs
		873899 RND3_HUMAN (4-227): 3.64e-100: 292: 64.00		S12A2_HUMAN (1-1212): 0: 1285: 100.00
+	Hs
		873960 RND1_HUMAN (6-227): 1.9e-83: 249: 53.15		S12A2_HUMAN (1-1212): 0: 1285: 100.00
+	Hs
		873898 RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03		S12A2_HUMAN (1-1212): 0: 1285: 100.00
+	Hs
		436225 RHOC_HUMAN (9-193): 3.15e-81: 242: 48.11		S12A2_HUMAN (1-1212): 0: 1285: 100.00
+	Hs
		873903 RAC1_HUMAN (8-194): 1.25e-78: 235: 42.25		S12A2_HUMAN (1-1212): 0: 1285: 100.00
+	Hs
		873901 RB11A_HUMAN (3-224): 7.25e-77: 232: 21.08		S12A2_HUMAN (1-1212): 0: 1285: 100.00
+	Hs
		852677 RND2_HUMAN (1-227): 7.71e-110: 316: 100.00		S12A4_HUMAN (167-1212): 0: 914: 23.71
+	Hs
		852696 RND2_HUMAN (1-227): 7.71e-110: 316: 100.00		S12A7_HUMAN (163-1212): 0: 874: 22.62
+	Hs
		901286 RND3_HUMAN (4-227): 3.64e-100: 292: 64.00		S12A7_HUMAN (163-1212): 0: 874: 22.62
+	Hs
		1269255 RND1_HUMAN (6-227): 1.9e-83: 249: 53.15		S12A4_HUMAN (167-1212): 0: 914: 23.71
+	Hs
		901055 RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03		S12A4_HUMAN (167-1212): 0: 914: 23.71
+	Hs
		436575 RHOC_HUMAN (9-193): 3.15e-81: 242: 48.11		S12A4_HUMAN (167-1212): 0: 914: 23.71
+	Hs
		925735 RAC1_HUMAN (8-194): 1.25e-78: 235: 42.25		S12A4_HUMAN (167-1212): 0: 914: 23.71
+	Hs
		1269266 RND1_HUMAN (6-227): 1.9e-83: 249: 53.15		S12A7_HUMAN (163-1212): 0: 874: 22.62
+	Hs
		901099 RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03		S12A7_HUMAN (163-1212): 0: 874: 22.62
+	Hs
		436596 RHOC_HUMAN (9-193): 3.15e-81: 242: 48.11		S12A7_HUMAN (163-1212): 0: 874: 22.62
+	Hs
		925769 RAC1_HUMAN (8-194): 1.25e-78: 235: 42.25		S12A7_HUMAN (163-1212): 0: 874: 22.62
+	Mm
		1265035 RAB1B_MOUSE (2-224): 1.4e-78: 236: 20.09		S12A5_MOUSE (188-1212): 0: 851: 22.08
+	Hs
		900749 RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03		YLAT2_HUMAN (248-776): 1.22e-113: 366: 11.49
+	Hs
		925480 RAC1_HUMAN (8-194): 1.25e-78: 235: 42.25		YLAT2_HUMAN (248-776): 1.22e-113: 366: 11.49