HitPredict

Interactor 1: RND2 (P52198)
Rho-related GTP-binding protein RhoN (Rho family GTPase 2) (Rho-related GTP-binding protein Rho7) (Rnd2)
Gene: RND2

Interactor 2: RAB8A (P61006)
Ras-related protein Rab-8A (EC 3.6.5.2) (Oncogene c-mel)
Gene: RAB8A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 227 Hs			1 207
+	Hs
		852496 RND2_HUMAN (1-227): 7.71e-110: 316: 100.00		RB11B_HUMAN (4-204): 1.1e-88: 261: 41.63
+	Hs
		852425 RND2_HUMAN (1-227): 7.71e-110: 316: 100.00		RAB1A_HUMAN (1-204): 1.23e-87: 258: 54.41
+	Hs
		895549 RAB1B_HUMAN (2-224): 3.11e-79: 237: 19.64		RAB10_HUMAN (3-181): 4.07e-93: 272: 75.98
+	Hs
		900511 RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03		RB11B_HUMAN (4-204): 1.1e-88: 261: 41.63
+	Hs
		900355 RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03		RAB1A_HUMAN (1-204): 1.23e-87: 258: 54.41
+	Zm
		73944 B4FAE1_MAIZE (2-225): 1.37e-82: 246: 20.44		B4FAE1_MAIZE (1-205): 3e-88: 259: 53.17
+	Hs
		900882 RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03		RAB1B_HUMAN (1-204): 7.39e-87: 256: 51.96
+	Hs
		894710 RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03		RAB8A_HUMAN (1-207): 1.67e-86: 255: 100.00
+	Hs
		918879 RAB1A_HUMAN (2-224): 4.55e-80: 240: 19.20		RB11B_HUMAN (4-204): 1.1e-88: 261: 41.63
+	Hs
		436244 RHOC_HUMAN (9-193): 3.15e-81: 242: 48.11		RAB1A_HUMAN (1-204): 1.23e-87: 258: 54.41
+	Hs
		845881 RAB1B_HUMAN (2-224): 3.11e-79: 237: 19.64		RAB13_HUMAN (1-206): 3.19e-89: 262: 61.17
+	Hs
		1079964 RAB1B_HUMAN (2-224): 3.11e-79: 237: 19.64		RB11B_HUMAN (4-204): 1.1e-88: 261: 41.63
+	Hs
		436498 RHOC_HUMAN (9-193): 3.15e-81: 242: 48.11		RAB1B_HUMAN (1-204): 7.39e-87: 256: 51.96
+	Hs
		918846 RAB1A_HUMAN (2-224): 4.55e-80: 240: 19.20		RAB1A_HUMAN (1-204): 1.23e-87: 258: 54.41
+	Hs
		436230 RHOC_HUMAN (9-193): 3.15e-81: 242: 48.11		RAB8A_HUMAN (1-207): 1.67e-86: 255: 100.00
+	Hs
		918944 RAB1A_HUMAN (2-224): 4.55e-80: 240: 19.20		RAB1B_HUMAN (1-204): 7.39e-87: 256: 51.96
+	Hs
		894715 RAB1A_HUMAN (2-224): 4.55e-80: 240: 19.20		RAB8A_HUMAN (1-207): 1.67e-86: 255: 100.00
+	Mm
		919000 RAB1A_MOUSE (2-224): 4.55e-80: 240: 19.20		RAB1B_MOUSE (1-204): 1.29e-86: 255: 51.96
+	Hs
		913992 RAB1A_HUMAN (2-224): 4.55e-80: 240: 19.20		RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06