HitPredict

Interactor 1: RND2 (P52198)
Rho-related GTP-binding protein RhoN (Rho family GTPase 2) (Rho-related GTP-binding protein Rho7) (Rnd2)
Gene: RND2

Interactor 2: EFNB1 (P98172)
Ephrin-B1 (EFL-3) (ELK ligand) (ELK-L) (EPH-related receptor tyrosine kinase ligand 2) (LERK-2) [Cleaved into: Ephrin-B1 C-terminal fragment (Ephrin-B1 CTF); Ephrin-B1 intracellular domain (Ephrin-B1 ICD)]
Gene: EFNB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 227 Hs			1 346
+	Hs
		901123 RND3_HUMAN (4-227): 3.64e-100: 292: 64.00		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		957902 RND1_HUMAN (6-227): 1.9e-83: 249: 53.15		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		900377 RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		436254 RHOC_HUMAN (9-193): 3.15e-81: 242: 48.11		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		925193 RAC1_HUMAN (8-194): 1.25e-78: 235: 42.25		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		914008 RB11A_HUMAN (3-224): 7.25e-77: 232: 21.08		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		892317 RAC3_HUMAN (8-182): 2.88e-76: 230: 42.86		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		545322 RAC2_HUMAN (8-195): 4.31e-76: 229: 40.43		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		950924 RHOG_HUMAN (7-193): 2.82e-75: 227: 41.71		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		856518 RND3_HUMAN (4-227): 3.64e-100: 292: 64.00		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		915606 RHOB_HUMAN (7-184): 9.27e-58: 182: 46.63		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		120388 RHOD_HUMAN (9-191): 9.02e-55: 176: 43.48		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		957940 RHOF_HUMAN (9-191): 9.16e-51: 165: 43.01		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		856517 RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		856523 RAC1_HUMAN (8-194): 1.25e-78: 235: 42.25		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		856521 RB11A_HUMAN (3-224): 7.25e-77: 232: 21.08		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		856514 RAC3_HUMAN (8-182): 2.88e-76: 230: 42.86		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		856522 RHOB_HUMAN (7-184): 9.27e-58: 182: 46.63		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		856572 RHOF_HUMAN (9-191): 9.16e-51: 165: 43.01		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		856359 RAC1_HUMAN (8-194): 1.25e-78: 235: 42.25		EFNA4_HUMAN (13-211): 5.6e-53: 175: 23.42