Interactor 1: HCXA (P45579)
Hydroxycarboxylate dehydrogenase A (EC 1.1.1.-) (2-oxobutanoate reductase) (2-oxoglutarate reductase)
Gene: HCXA
Interactor 2: HCXA (P45579)
Hydroxycarboxylate dehydrogenase A (EC 1.1.1.-) (2-oxobutanoate reductase) (2-oxoglutarate reductase)
Gene: HCXA
Species: Escherichia coli K-12
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.56 | 1.00 | 0.752 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24561554 |
| Identification Methods | two hybrid, affinity chromatography technology, two hybrid array, luminescence based mammalian interactome mapping |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Fe-ADH~Fe-ADH |
| Common GO terms | GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0046872 - metal ion binding GO:0047545 - 2-hydroxyglutarate dehydrogenase activity |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
