HitPredict

Interactor 1: IMA5 (P52294)
Importin subunit alpha-5 (Karyopherin subunit alpha-1) (Nucleoprotein interactor 1) (NPI-1) (RAG cohort protein 2) (SRP1-beta) [Cleaved into: Importin subunit alpha-5, N-terminally processed]
Gene: KPNA1

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Arm~Ras, Arm_3~Ras
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 538 Hs			1 196
+	Hs
		238654 IMA7_HUMAN (1-538): 6.51e-160: 467: 80.48		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		853562 IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		134868 IMA3_HUMAN (1-538): 7e-156: 456: 45.84		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		853556 IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		545276 IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		436216 IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		853554 IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		853234 IMA1_HUMAN (3-538): 1.64e-149: 441: 44.36		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		853228 IMA1_HUMAN (3-538): 1.64e-149: 441: 44.36		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		853220 IMA1_HUMAN (3-538): 1.64e-149: 441: 44.36		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49