HitPredict

Interactor 1: IMA5 (P52294)
Importin subunit alpha-5 (Karyopherin subunit alpha-1) (Nucleoprotein interactor 1) (NPI-1) (RAG cohort protein 2) (SRP1-beta) [Cleaved into: Importin subunit alpha-5, N-terminally processed]
Gene: KPNA1

Interactor 2: KAT5 (Q92993)
Histone acetyltransferase KAT5 (EC 2.3.1.48) (60 kDa Tat-interactive protein) (Tip60) (Histone acetyltransferase HTATIP) (HIV-1 Tat interactive protein) (Lysine acetyltransferase 5) (Protein 2-hydroxyisobutyryltransferase KAT5) (EC 2.3.1.-) (Protein acetyltransferase KAT5) (EC 2.3.1.-) (Protein crotonyltransferase KAT5) (EC 2.3.1.-) (cPLA(2)-interacting protein)
Gene: KAT5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0042981 - regulation of apoptotic process
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 538 Hs			1 513
+	Hs
		238718 IMA7_HUMAN (1-538): 6.51e-160: 467: 80.48		KAT5_HUMAN (1-513): 0: 852: 100.00
+	Hs
		134944 IMA3_HUMAN (1-538): 7e-156: 456: 45.84		KAT5_HUMAN (1-513): 0: 852: 100.00
+	Hs
		168661 IMA6_HUMAN (1-538): 1.39e-152: 449: 79.59		KAT5_HUMAN (1-513): 0: 852: 100.00
+	Hs
		131483 IMA4_HUMAN (3-538): 1.73e-150: 443: 45.91		KAT5_HUMAN (1-513): 0: 852: 100.00
+	Dm
		1280426 Q9V455_DROME (4-538): 9.55e-147: 433: 44.49		TIP60_DROME (7-512): 0: 709: 57.60
+	Hs
		853403 IMA1_HUMAN (3-538): 1.64e-149: 441: 44.36		KAT6A_HUMAN (70-504): 1.5e-138: 442: 37.23
+	Sc
		972927 IMA1_YEAST (2-538): 8.07e-143: 424: 49.26		ESA1_YEAST (21-103): 6e-11: 66.3: 38.10