HitPredict

Interactor 1: IMA (P52295)
Importin subunit alpha (Karyopherin subunit alpha) (Pendulin)
Gene: Pen

Interactor 2: XPO2 (Q9XZU1)
Exportin-2 (Exp2) (Cellular apoptosis susceptibility protein homolog) (Chromosome segregation protein 1) (Importin-alpha re-exporter)
Gene: Cse1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.80	0.587

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Arm~Cse1, Arm_3~CAS_CSE1, Arm_3~Cse1, Cse1~IBB, IBB~IBN_N
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 522 Dm			1 975
+	Hs
		134861 IMA3_HUMAN (6-522): 1.08e-144: 427: 45.84		XPO2_HUMAN (1-974): 0: 677: 51.33
+	Dm
		283985 O76521_DROME (9-522): 3.88e-137: 409: 40.99		XPO2_DROME (1-975): 0: 692: 100.00
+	Hs
		853218 IMA1_HUMAN (8-522): 3.38e-139: 414: 49.04		XPO2_HUMAN (1-974): 0: 677: 51.33
+	Hs
		853551 IMA5_HUMAN (2-521): 3.58e-126: 381: 42.75		XPO2_HUMAN (1-974): 0: 677: 51.33
+	Sc
		704136 IMA1_YEAST (7-522): 4.1e-132: 396: 40.34		CSE1_YEAST (6-967): 4.02e-169: 521: 32.96
+	Hs
		134943 IMA3_HUMAN (6-522): 1.08e-144: 427: 45.84		TNPO1_HUMAN (16-967): 5.58e-157: 487: 11.51
+	Hs
		312219 IMA1_HUMAN (8-522): 3.38e-139: 414: 49.04		IPO7_HUMAN (9-975): 1.4e-159: 498: 17.00
+	Hs
		853409 IMA1_HUMAN (8-522): 3.38e-139: 414: 49.04		TNPO1_HUMAN (16-967): 5.58e-157: 487: 11.51
+	Xl
		193806 Q7ZYI0_XENLA (1-520): 2.94e-137: 408: 47.92		O42480_XENLA (11-975): 3.42e-155: 487: 17.03
+	At
		1280912 IMPA1_ARATH (2-522): 3.41e-152: 447: 43.21		IMB1_ARATH (10-840): 1.2e-122: 396: 12.59
+	At
		97814 IMPA2_ARATH (2-522): 5.06e-148: 436: 43.26		IMB1_ARATH (10-840): 1.2e-122: 396: 12.59
+	Dm
		1359635 Q9V455_DROME (1-522): 2.41e-132: 396: 43.68		IPO9_DROME (2-872): 8.26e-125: 406: 14.53
+	Sp
		143432 IMA2_SCHPO (1-522): 3.43e-132: 396: 40.52		IMB1_SCHPO (13-890): 1.37e-125: 403: 13.13
+	Hs
		131341 IMA4_HUMAN (2-522): 1.47e-141: 419: 44.53		XPO1_HUMAN (4-966): 1.22e-109: 366: 12.53
+	Hs
		162530 IMA1_HUMAN (8-522): 3.38e-139: 414: 49.04		XPO1_HUMAN (4-966): 1.22e-109: 366: 12.53
+	Sp
		144310 IMA2_SCHPO (1-522): 3.43e-132: 396: 40.52		IMB2_SCHPO (3-965): 2.5e-108: 359: 11.18
+	Dm
		185867 O76522_DROME (1-522): 1.88e-132: 396: 43.68		IMB_DROME (10-840): 3.09e-108: 358: 12.81
+	Dm
		185896 Q9V455_DROME (1-522): 2.41e-132: 396: 43.68		IMB_DROME (10-840): 3.09e-108: 358: 12.81
+	Dm
		185871 IMA_DROME (1-522): 4.32e-127: 382: 100.00		IMB_DROME (10-840): 3.09e-108: 358: 12.81