HitPredict

Interactor 1: NCBP2 (P52298)
Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (Cell proliferation-inducing gene 55 protein) (NCBP 20 kDa subunit) (CBP20) (NCBP-interacting protein 1) (NIP1)
Gene: NCBP2

Interactor 2: PABP4 (Q13310)
Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)
Gene: PABPC4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	32960270
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 156 Hs			1 644
+	Hs
		516425 NCBP2_HUMAN (1-156): 2.27e-48: 154: 100.00		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		516495 PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41		PABP4_HUMAN (1-644): 0: 585: 100.00
+	Hs
		1020249 ELAV2_HUMAN (33-122): 1.29e-25: 101: 21.11		PABP4_HUMAN (1-644): 0: 585: 100.00
+	Hs
		1031344 ELAV1_HUMAN (7-123): 1.27e-24: 98.4: 18.49		PABP4_HUMAN (1-644): 0: 585: 100.00
+	Hs
		516339 PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		516484 ELAV2_HUMAN (33-122): 1.29e-25: 101: 21.11		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		516689 PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41		PABP3_HUMAN (1-644): 7.04e-175: 513: 68.98
+	Sc
		376958 NCBP2_YEAST (10-150): 3.97e-39: 132: 52.48		PABP_YEAST (2-290): 4.28e-66: 228: 30.07
+	Hs
		1020259 ELAV2_HUMAN (33-122): 1.29e-25: 101: 21.11		ELAV3_HUMAN (3-272): 2.13e-40: 153: 19.15
+	Hs
		474021 PABP4_HUMAN (4-156): 2.89e-27: 107: 17.18		PAB4L_HUMAN (192-380): 4.58e-38: 146: 31.05
+	Hs
		474019 ELAV2_HUMAN (33-122): 1.29e-25: 101: 21.11		PAB4L_HUMAN (192-380): 4.58e-38: 146: 31.05
+	Hs
		516355 PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41		NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82
+	Mm
		449421 ELAV1_MOUSE (7-125): 1.85e-24: 98: 19.01		NUCL_MOUSE (3-89): 2.31e-20: 97.6: 31.03
+	Hs
		516635 PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41		PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33
+	Hs
		1020306 ELAV2_HUMAN (33-122): 1.29e-25: 101: 21.11		PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33
+	Mm
		665745 PABP1_MOUSE (4-156): 7.6e-28: 109: 18.41		TIA1_MOUSE (4-86): 1.26e-12: 72: 30.12
+	Hs
		1055876 ELAV3_HUMAN (5-122): 3.32e-24: 98: 16.67		PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33
+	Mm
		857310 ELAV1_MOUSE (7-125): 1.85e-24: 98: 19.01		TIA1_MOUSE (4-86): 1.26e-12: 72: 30.12
+	Hs
		680455 ELAV1_HUMAN (7-123): 1.27e-24: 98.4: 18.49		TIA1_HUMAN (4-109): 7.62e-12: 69.5: 24.53