HitPredict

Interactor 1: NCBP2 (P52298)
Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (Cell proliferation-inducing gene 55 protein) (NCBP 20 kDa subunit) (CBP20) (NCBP-interacting protein 1) (NIP1)
Gene: NCBP2

Interactor 2: MINT (Q96T58)
Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog)
Gene: SPEN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003677 - DNA binding GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 156 Hs			1 3664
+	Sc
		376958 NCBP2_YEAST (10-150): 3.97e-39: 132: 52.48		PABP_YEAST (315-850): 1.52e-86: 298: 13.13
+	Hs
		516635 PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41		PABP5_HUMAN (339-684): 1.68e-86: 291: 19.21
+	Hs
		1020306 ELAV2_HUMAN (33-122): 1.29e-25: 101: 21.11		PABP5_HUMAN (339-684): 1.68e-86: 291: 19.21
+	Hs
		1055876 ELAV3_HUMAN (5-122): 3.32e-24: 98: 16.67		PABP5_HUMAN (339-684): 1.68e-86: 291: 19.21
+	Hs
		516471 PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41		TIAR_HUMAN (321-515): 4.05e-44: 168: 21.08
+	Hs
		963526 ELAV1_HUMAN (7-123): 1.27e-24: 98.4: 18.49		TIAR_HUMAN (321-515): 4.05e-44: 168: 21.08
+	Mm
		665745 PABP1_MOUSE (4-156): 7.6e-28: 109: 18.41		TIA1_MOUSE (293-512): 1.64e-37: 149: 17.47
+	Hs
		680455 ELAV1_HUMAN (7-123): 1.27e-24: 98.4: 18.49		TIA1_HUMAN (293-512): 4.75e-41: 159: 17.47
+	Hs
		853881 NCBP2_HUMAN (1-156): 2.27e-48: 154: 100.00		PABP4_HUMAN (6-131): 2.64e-15: 84.9: 15.03
+	Hs
		516425 NCBP2_HUMAN (1-156): 2.27e-48: 154: 100.00		PABP1_HUMAN (6-156): 2.77e-09: 65.2: 13.48
+	Hs
		474021 PABP4_HUMAN (4-156): 2.89e-27: 107: 17.18		PAB4L_HUMAN (6-165): 1.39e-18: 93: 13.09
+	Hs
		516766 PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41		PRC2C_HUMAN (1490-3644): 8.69e-16: 87.2: 7.55
+	Hs
		474019 ELAV2_HUMAN (33-122): 1.29e-25: 101: 21.11		PAB4L_HUMAN (6-165): 1.39e-18: 93: 13.09
+	Hs
		516495 PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41		PABP4_HUMAN (6-131): 2.64e-15: 84.9: 15.03
+	Hs
		1020249 ELAV2_HUMAN (33-122): 1.29e-25: 101: 21.11		PABP4_HUMAN (6-131): 2.64e-15: 84.9: 15.03
+	Hs
		516689 PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41		PABP3_HUMAN (215-439): 8.48e-13: 76.8: 11.89
+	Hs
		1031344 ELAV1_HUMAN (7-123): 1.27e-24: 98.4: 18.49		PABP4_HUMAN (6-131): 2.64e-15: 84.9: 15.03
+	Hs
		516339 PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41		PABP1_HUMAN (6-156): 2.77e-09: 65.2: 13.48
+	Hs
		516484 ELAV2_HUMAN (33-122): 1.29e-25: 101: 21.11		PABP1_HUMAN (6-156): 2.77e-09: 65.2: 13.48