HitPredict

Interactor 1: GDS1 (P52306)
Rap1 GTPase-GDP dissociation stimulator 1 (Exchange factor smgGDS) (SMG GDS protein) (SMG P21 stimulatory GDP/GTP exchange protein)
Gene: RAP1GDS1

Interactor 2: RHES (Q96D21)
GTP-binding protein Rhes (Ras homolog enriched in striatum) (Tumor endothelial marker 2)
Gene: RASD2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	26186194
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Arm~Ras
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 607 Hs			1 266
+	Hs
		854133 GDS1_HUMAN (1-607): 0: 917: 100.00		RAB1B_HUMAN (12-219): 3.33e-77: 234: 21.23
+	Hs
		854121 GDS1_HUMAN (1-607): 0: 917: 100.00		DIRA2_HUMAN (18-191): 1.41e-38: 135: 43.10
+	Hs
		303756 GDS1_HUMAN (1-607): 0: 917: 100.00		DIRA1_HUMAN (18-189): 5.94e-33: 120: 44.19
+	Hs
		854082 GDS1_HUMAN (1-607): 0: 917: 100.00		RAP1B_HUMAN (20-186): 3.33e-31: 115: 39.52
+	Hs
		854088 GDS1_HUMAN (1-607): 0: 917: 100.00		RAP1A_HUMAN (20-186): 1.5e-30: 114: 39.52
+	Hs
		488066 GDS1_HUMAN (1-607): 0: 917: 100.00		RRAS_HUMAN (32-183): 4.18e-27: 106: 42.11
+	Hs
		854083 GDS1_HUMAN (1-607): 0: 917: 100.00		RAP2B_HUMAN (32-183): 2.07e-26: 103: 39.87
+	Hs
		506444 GDS1_HUMAN (1-607): 0: 917: 100.00		RALB_HUMAN (1-186): 1.85e-25: 101: 34.41
+	Hs
		854154 GDS1_HUMAN (1-607): 0: 917: 100.00		RAP2C_HUMAN (32-183): 4.1e-25: 100: 39.47
+	Hs
		854086 GDS1_HUMAN (1-607): 0: 917: 100.00		RRAS2_HUMAN (16-203): 2.12e-24: 98.6: 38.54
+	Xl
		292765 GDS1A_XENLA (1-607): 0: 899: 85.50		RALBA_XENLA (20-186): 8.29e-25: 99.8: 36.53
+	Xl
		292764 GDS1A_XENLA (1-607): 0: 899: 85.50		RALBB_XENLA (20-186): 1.54e-24: 99: 35.93