HitPredict

Interactor 1: GDS1 (P52306)
Rap1 GTPase-GDP dissociation stimulator 1 (Exchange factor smgGDS) (SMG GDS protein) (SMG P21 stimulatory GDP/GTP exchange protein)
Gene: RAP1GDS1

Interactor 2: RASLC (Q9NYN1)
Ras-like protein family member 12 (EC 3.6.5.2) (Ras-like protein Ris)
Gene: RASL12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Arm~Ras
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 607 Hs			1 266
+	Hs
		854133 GDS1_HUMAN (1-607): 0: 917: 100.00		RAB1B_HUMAN (13-219): 2.69e-86: 257: 21.53
+	Hs
		854088 GDS1_HUMAN (1-607): 0: 917: 100.00		RAP1A_HUMAN (20-192): 4.44e-24: 97.4: 34.86
+	Hs
		854082 GDS1_HUMAN (1-607): 0: 917: 100.00		RAP1B_HUMAN (20-192): 8.98e-24: 96.3: 34.86
+	Hs
		488066 GDS1_HUMAN (1-607): 0: 917: 100.00		RRAS_HUMAN (33-195): 4.95e-23: 95.5: 34.50
+	Hs
		854126 GDS1_HUMAN (1-607): 0: 917: 100.00		RSLBB_HUMAN (21-190): 2.15e-22: 94.4: 31.29
+	Hs
		854083 GDS1_HUMAN (1-607): 0: 917: 100.00		RAP2B_HUMAN (33-182): 8.11e-23: 94: 37.75
+	Hs
		854086 GDS1_HUMAN (1-607): 0: 917: 100.00		RRAS2_HUMAN (33-195): 1.52e-22: 93.6: 35.12
+	Hs
		854154 GDS1_HUMAN (1-607): 0: 917: 100.00		RAP2C_HUMAN (33-182): 2.79e-22: 92.4: 37.75
+	Dm
		51787 GDS1_DROME (62-536): 0: 540: 31.27		O96692_DROME (33-182): 1.26e-23: 95.9: 40.40