HitPredict

Interactor 1: JAK3 (P52333)
Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)
Gene: JAK3

Interactor 2: TBA4A (P68366)
Tubulin alpha-4A chain (EC 3.6.5.-) (Alpha-tubulin 1) (Testis-specific alpha-tubulin) (Tubulin H2-alpha) (Tubulin alpha-1 chain)
Gene: TUBA4A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1124 Hs			1 448
+	Hs
		522895 SRC_HUMAN (793-1109): 4.7e-100: 328: 29.25		TBA4A_HUMAN (1-448): 0: 724: 100.00
+	Hs
		522894 SRC_HUMAN (793-1109): 4.7e-100: 328: 29.25		TBA1B_HUMAN (1-439): 0: 715: 97.49
+	Hs
		427991 SRC_HUMAN (793-1109): 4.7e-100: 328: 29.25		TBB5_HUMAN (1-439): 0: 697: 40.55
+	Hs
		433849 LYN_HUMAN (781-1110): 2.14e-92: 307: 28.40		TBA1A_HUMAN (1-439): 0: 712: 97.04
+	Hs
		411549 LCK_HUMAN (794-1110): 1.37e-97: 321: 30.50		TBB5_HUMAN (1-439): 0: 697: 40.55
+	Hs
		411668 LCK_HUMAN (794-1110): 1.37e-97: 321: 30.50		TBB4B_HUMAN (1-437): 0: 695: 40.28
+	Hs
		428098 BLK_HUMAN (784-1105): 3.14e-89: 298: 29.63		TBB5_HUMAN (1-439): 0: 697: 40.55
+	Gg
		94426 KSYK_CHICK (527-773): 4.4e-18: 91.7: 26.95		TBA2_CHICK (1-446): 0: 783: 83.41
+	Hs
		669157 TYK2_HUMAN (828-1122): 5.53e-34: 144: 20.62		TBA4A_HUMAN (1-448): 0: 724: 100.00
+	Hs
		338265 EGFR_HUMAN (527-780): 3.22e-18: 92.8: 24.34		TBA4A_HUMAN (1-448): 0: 724: 100.00
+	Mm
		815725 KSYK_MOUSE (520-773): 7.4e-18: 90.9: 27.38		TBA4A_MOUSE (1-448): 0: 724: 100.00
+	Hs
		338607 EGFR_HUMAN (527-780): 3.22e-18: 92.8: 24.34		TBA1A_HUMAN (1-439): 0: 712: 97.04
+	Hs
		796466 ZAP70_HUMAN (527-773): 4.08e-17: 88.6: 28.02		TBA1B_HUMAN (1-439): 0: 715: 97.49
+	Hs
		796597 KSYK_HUMAN (525-773): 5e-18: 91.3: 27.13		TBA1A_HUMAN (1-439): 0: 712: 97.04
+	Hs
		796477 ZAP70_HUMAN (527-773): 4.08e-17: 88.6: 28.02		TBA1A_HUMAN (1-439): 0: 712: 97.04
+	Hs
		337782 EGFR_HUMAN (527-780): 3.22e-18: 92.8: 24.34		TBB5_HUMAN (1-439): 0: 697: 40.55
+	Gg
		94429 KSYK_CHICK (527-773): 4.4e-18: 91.7: 26.95		TBB7_CHICK (1-439): 0: 697: 40.55
+	Hs
		428078 KSYK_HUMAN (525-773): 5e-18: 91.3: 27.13		TBB5_HUMAN (1-439): 0: 697: 40.55
+	Hs
		338266 EGFR_HUMAN (527-780): 3.22e-18: 92.8: 24.34		TBB4B_HUMAN (1-437): 0: 695: 40.28
+	Hs
		428077 ZAP70_HUMAN (527-773): 4.08e-17: 88.6: 28.02		TBB5_HUMAN (1-439): 0: 697: 40.55