HitPredict

Interactor 1: JAK3 (P52333)
Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)
Gene: JAK3

Interactor 2: RB11B (Q15907)
Ras-related protein Rab-11B (EC 3.6.5.2) (GTP-binding protein YPT3)
Gene: RAB11B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26496610
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1124 Hs			1 218
+	Hs
		854167 JAK3_HUMAN (1-1124): 0: 968: 100.00		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		523004 SRC_HUMAN (793-1109): 4.7e-100: 328: 29.25		RB11B_HUMAN (1-218): 2.77e-95: 278: 100.00
+	Hs
		522882 SRC_HUMAN (793-1109): 4.7e-100: 328: 29.25		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		433312 YES_HUMAN (784-1109): 7.17e-99: 326: 29.36		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		433302 YES_HUMAN (784-1109): 7.17e-99: 326: 29.36		RAB25_HUMAN (2-218): 1.3e-83: 249: 60.63
+	Hs
		522878 SRC_HUMAN (793-1109): 4.7e-100: 328: 29.25		RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56
+	Hs
		433306 YES_HUMAN (784-1109): 7.17e-99: 326: 29.36		RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56
+	Hs
		433674 LYN_HUMAN (781-1110): 2.14e-92: 307: 28.40		RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56
+	Hs
		338238 EGFR_HUMAN (527-780): 3.22e-18: 92.8: 24.34		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		338247 EGFR_HUMAN (527-780): 3.22e-18: 92.8: 24.34		RAB1A_HUMAN (1-215): 2.92e-90: 265: 43.26
+	Hs
		338205 EGFR_HUMAN (527-780): 3.22e-18: 92.8: 24.34		RAB25_HUMAN (2-218): 1.3e-83: 249: 60.63
+	Hs
		383971 ERBB2_HUMAN (527-780): 1.84e-13: 77.4: 25.00		RAB1B_HUMAN (4-215): 8.36e-87: 256: 44.81