HitPredict

Interactor 1: RPAB3 (P52434)
DNA-directed RNA polymerases I, II, and III subunit RPABC3 (RNA polymerases I, II, and III subunit ABC3) (DNA-directed RNA polymerase II subunit H) (DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide) (RPB17) (RPB8 homolog) (hRPB8)
Gene: POLR2H

Interactor 2: RPC2 (Q9NW08)
DNA-directed RNA polymerase III subunit RPC2 (RNA polymerase III subunit C2) (EC 2.7.7.6) (C128) (DNA-directed RNA polymerase III 127.6 kDa polypeptide) (DNA-directed RNA polymerase III subunit B)
Gene: POLR3B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	35271311, 33674783, 24981860
Identification Methods	affinity chromatography technology, biochemical, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001056 - RNA polymerase III activity GO:0005654 - nucleoplasm GO:0005666 - RNA polymerase III complex GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 150 Hs			1 1133
+	Hs
		676841 RPAB3_HUMAN (1-150): 1.61e-78: 231: 100.00		RPB2_HUMAN (14-1127): 0: 1475: 37.52
+	Sc
		593278 RPAB3_YEAST (1-147): 2.38e-48: 154: 35.07		RPC2_YEAST (12-1130): 0: 1471: 62.84
+	Sc
		439969 RPAB3_YEAST (1-147): 2.38e-48: 154: 35.07		RPB2_YEAST (13-1130): 0: 1382: 36.70
+	Sp
		968762 RPAB3_SCHPO (4-147): 5.15e-41: 135: 36.81		RPB2_SCHPO (19-1131): 0: 1388: 34.93
+	Hs
		854370 RPAB3_HUMAN (1-150): 1.61e-78: 231: 100.00		RPA2_HUMAN (36-1128): 0: 1159: 29.59
+	Sc
		593276 RPAB3_YEAST (1-147): 2.38e-48: 154: 35.07		RPA2_YEAST (12-1129): 0: 1047: 28.42